Key features and details
- Rabbit polyclonal to Annexin-2/ANXA2 (phospho S26)
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
Product nameAnti-Annexin-2/ANXA2 (phospho S26) antibody
See all Annexin-2/ANXA2 primary antibodies
DescriptionRabbit polyclonal to Annexin-2/ANXA2 (phospho S26)
ab192593 detects endogenous levels of Annexin-2/ANXA2 only when phosphorylated at serine 26.
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide corresponding to Human Annexin-2/ANXA2 (phospho S26) conjugated to keyhole limpet haemocyanin.
Database link: P07355
- Extracts from HepG2, Jurkat and K562 cells.
This product was previously labelled as Annexin A2
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 49% PBS, 50% Glycerol (glycerin, glycerine), 0.87% Sodium chloride
PBS is without Mg2+ and Ca2+.
Concentration information loading...
PurityImmunogen affinity purified
Purification notesab192593 was purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Our Abpromise guarantee covers the use of ab192593 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/1000. Predicted molecular weight: 39 kDa.|
FunctionCalcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.
Sequence similaritiesBelongs to the annexin family.
Contains 4 annexin repeats.
DomainA pair of annexin repeats may form one binding site for calcium and phospholipid.
modificationsPhosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface.
Cellular localizationSecreted > extracellular space > extracellular matrix > basement membrane. Melanosome. In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the cell surface through a Golgi-independent mechanism.
- Information by UniProt
- Annexin A2 antibody
- Annexin II antibody
- Annexin II, heavy chain antibody
ab192593 has not yet been referenced specifically in any publications.