APC Anti-CCR7 antibody [4B12] (ab93518)
![Flow Cytometry - APC Anti-CCR7 antibody [4B12] (ab93518)](https://www.abcam.com/ps/products/93/ab93518/Images/ab93518-108556-anti-ccr7-antibody-4b12-allophycocyanin-flow-cytometry.jpg "Flow Cytometry - APC Anti-CCR7 antibody [4B12] (ab93518)")
Key features and details
- APC Rat monoclonal [4B12] to CCR7
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG2a
Related conjugates and formulations
Overview
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Product name
APC Anti-CCR7 antibody [4B12]
See all CCR7 primary antibodies -
Description
APC Rat monoclonal [4B12] to CCR7 -
Host species
Rat -
Conjugation
APC. Ex: 645nm, Em: 660nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Mouse -
Immunogen
Tissue, cells or virus corresponding to CCR7. Rat basophilic leukaemia (RBL)-2H3 cells transfectanted with Mouse CCR7.
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Positive control
- C57Bl/6 splenocytes
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 0.87% Sodium chloride, PBS -
Concentration information loading... -
Purity
Affinity purified -
Clonality
Monoclonal -
Clone number
4B12 -
Isotype
IgG2a -
Light chain type
kappa -
Research areas
Associated products
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Alternative Versions
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab93518 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt |
Use 1µg for 106 cells.
|
| Notes |
|---|
|
Flow Cyt
Use 1µg for 106 cells. |
Target
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Function
Receptor for the MIP-3-beta chemokine. Probable mediator of EBV effects on B-lymphocytes or of normal lymphocyte functions. -
Tissue specificity
Expressed in various lymphoid tissues and activated B- and T-lymphocytes, strongly up-regulated in B-cells infected with Epstein-Barr virus and T-cells infected with herpesvirus 6 or 7. -
Sequence similarities
Belongs to the G-protein coupled receptor 1 family. -
Cellular localization
Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 12775 Mouse
- SwissProt: P47774 Mouse
- Unigene: 2932 Mouse
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Alternative names
- BLR 2 antibody
- BLR2 antibody
- C C chemokine receptor type 7 antibody
see all
Images
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Flow Cytometry - APC Anti-CCR7 antibody [4B12] (ab93518)Staining of C57Bl/6 splenocytes with FITC anti-mouse CD4 (GK1.5) and either 0.5 µg of ab93518 (right) or 0.5 µg of APC Rat IgG2a Iso Control (left). Cells were stained at 37°C for 0.5 hours and Fc receptor binding was blocked by staining cells with 5 µg/million cells anti-mouse CD16/32. Cells in the lymphocyte gate were used for analysis.
Datasheets and documents
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Datasheet download
References (0)
ab93518 has not yet been referenced specifically in any publications.
