Key features and details
- APC Mouse monoclonal [MEM-166] to CD177
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG1
Product nameAPC Anti-CD177 antibody [MEM-166]
See all CD177 primary antibodies
DescriptionAPC Mouse monoclonal [MEM-166] to CD177
ConjugationAPC. Ex: 645nm, Em: 660nm
Species reactivityReacts with: Human
Predicted to work with: Non human primates
- Human blood cells.
Purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.4
Preservative: 0.097% Sodium azide
Constituent: 0.2% BSA
0.2% (w/v) high-grade protease free BSA
Concentration information loading...
Purification notesThe conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
Tissue specificityHighly expressed in normal bone marrow and weakly expressed in fetal liver. Expressed on neutrophils. Expressed in granulocytes of patients with polycythemia vera (PV) and with essential thrombocythemia (ET).
Sequence similaritiesContains 2 UPAR/Ly6 domains.
A soluble form may also be produced by proteolytic cleavage at the cell surface (shedding).
Cellular localizationCell membrane.
- Information by UniProt
- CD177 antibody
- CD177 antigen antibody
- CD177 molecule antibody
ab77230 has been referenced in 3 publications.
- Liu H et al. Proteinase 3 expression on the neutrophils of patients with paroxysmal nocturnal hemoglobinuria. Exp Ther Med 15:2525-2532 (2018). PubMed: 29467851
- Meyerson HJ et al. CD177 expression on neutrophils: in search of a clonal assay for myeloid neoplasia by flow cytometry. Am J Clin Pathol 140:658-69 (2013). PubMed: 24124144
- Zhou J et al. CXCR3-dependent accumulation and activation of perivascular macrophages is necessary for homeostatic arterial remodeling to hemodynamic stresses. J Exp Med 207:1951-66 (2010). Flow Cyt ; Human . PubMed: 20733031