APC Anti-CD2 antibody [T6.3] (ab52003)

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Key features and details

  • APC Mouse monoclonal [T6.3] to CD2
  • Reacts with: Human
  • Conjugation: APC. Ex: 645nm, Em: 660nm
  • Isotype: IgG2a

Overview

  • Product name

    APC Anti-CD2 antibody [T6.3]
    See all CD2 primary antibodies

  • Description

    APC Mouse monoclonal [T6.3] to CD2

  • Host species

    Mouse

  • Conjugation

    APC. Ex: 645nm, Em: 660nm

  • Specificity

    Detects human T cells and subset of NK cells associated with the receptor for sheep erythocytes rosettes expressing the 45-50,000 M.W. surface antigen.

  • Species reactivity

    Reacts with: Human

  • Immunogen

    Tissue, cells or virus corresponding to CD2.
    Database link: P06729

  • Positive control

    • Peripheral blood lymphocytes

  • General notes

    The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.

    If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As

Properties

Target

  • Function

    CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.

  • Sequence similarities

    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 Ig-like V-type (immunoglobulin-like) domain.

  • Cellular localization

    Membrane.
  • Information by UniProt

  • Database links

    • Alternative names

      • CD 2 antibody
      • CD2 antibody
      • CD2 antigen (p50), sheep red blood cell receptor antibody
      • CD2 antigen antibody
      • CD2 molecule antibody
      • CD2_HUMAN antibody
      • Erythrocyte receptor antibody
      • FLJ46032 antibody
      • LFA-2 antibody
      • LFA-3 receptor antibody
      • LFA2 antibody
      • LFA3 receptor antibody
      • Ly-37 antibody
      • Lymphocyte function antigen 2 antibody
      • lymphocyte-function antigen-2 antibody
      • OTTHUMP00000024366 antibody
      • Rosette receptor antibody
      • Sheep erythrocyte receptor antibody
      • SRBC antibody
      • T cell surface antigen CD2 antibody
      • T-cell surface antigen CD2 antibody
      • T-cell surface antigen T11/Leu-5 antibody
      • T-lymphocyte surface CD2 antigen antibody
      • T11 antibody
      see all

    References (1)

    Publishing research using ab52003? Please let us know so that we can cite the reference in this datasheet.

    ab52003 has been referenced in 1 publication.

    • COWAN KM Studies on the coliphage neutralizing activity of normal human serum. J Immunol 88:476-81 (1962). PubMed: 13881856

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