APC Anti-CD73 antibody [AD2], prediluted (ab155378)

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Flow Cytometry - APC Anti-CD73 antibody [AD2], prediluted (ab155378)

    Key features and details

    • APC Mouse monoclonal [AD2] to CD73, prediluted
    • Suitable for: Flow Cyt
    • Reacts with: Human
    • Conjugation: APC. Ex: 645nm, Em: 660nm
    • Isotype: IgG1

    Overview

    • Product name

      APC Anti-CD73 antibody [AD2], prediluted
      See all CD73 primary antibodies

    • Description

      APC Mouse monoclonal [AD2] to CD73, prediluted

    • Host species

      Mouse

    • Conjugation

      APC. Ex: 645nm, Em: 660nm

    • Tested applications

      Suitable for: Flow Cytmore details

    • Species reactivity

      Reacts with: Human

    • Immunogen

      The details of the immunogen for this antibody are not available.

    • Positive control

      • Normal Human peripheral blood cells.

    • General notes

      Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.

      Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.

      We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.

      In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.

      We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.

      Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.

      Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.

    Properties

    Applications

    Our Abpromise guarantee covers the use of ab155378 in the following tested applications.

    The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

    Application Abreviews Notes
    Flow Cyt Use 5µl for 106 cells.

    ab37391 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.

    Target

    • Function

      Hydrolyzes extracellular nucleotides into membrane permeable nucleosides.

    • Involvement in disease

      Defects in NT5E are the cause of calcification of joints and arteries (CAJA) [MIM:211800]. A condition characterized by adult-onset calcification of the lower extremity arteries, including the iliac, femoral and tibial arteries, and hand and foot capsule joints. Age of onset has been reported as early as the second decade of life, usually involving intense joint pain or calcification in the hands.

    • Sequence similarities

      Belongs to the 5'-nucleotidase family.

    • Cellular localization

      Cell membrane.
    • Information by UniProt

    • Database links

      • Alternative names

        • 5' NT antibody
        • 5' nucleotidase (CD73) antibody
        • 5' nucleotidase precursor antibody
        • 5' nucleotidase, ecto antibody
        • 5' nucleotidase, ecto (CD73) antibody
        • 5'-NT antibody
        • 5'-nucleotidase antibody
        • 5NTD_HUMAN antibody
        • CD73 antibody
        • CD73 antigen antibody
        • E5NT antibody
        • Ecto 5' nucleotidase antibody
        • Ecto-5'-nucleotidase antibody
        • eN antibody
        • eNT antibody
        • NT antibody
        • NT5 antibody
        • NT5E antibody
        • NTE antibody
        • Purine 5 Prime Nucleotidase antibody
        see all

      Images

      • Flow Cytometry - APC Anti-CD73 antibody [AD2], prediluted (ab155378)
        Flow Cytometry - APC Anti-CD73 antibody [AD2], prediluted (ab155378)
        Flow Cytometric analysis of normal Human peripheral blood cells labeling CD73 with ab155378 (purple histogram) at 0.125 µg/test in 100 µl final volume or an equal amount of Mouse IgG1 kappa Isotype Control APC (blue histogram). Cells in the lymphocyte gate were used for analysis.

      References (2)

      Publishing research using ab155378? Please let us know so that we can cite the reference in this datasheet.

      ab155378 has been referenced in 2 publications.

      • Queckbörner S  et al. Endometrial stromal cells exhibit a distinct phenotypic and immunomodulatory profile. Stem Cell Res Ther 11:15 (2020). PubMed: 31907034
      • Jensen J  et al. Functionalization of polycaprolactone scaffolds with hyaluronic acid and ß-TCP facilitates migration and osteogenic differentiation of human dental pulp stem cells in vitro. Tissue Eng Part A 21:729-39 (2015). PubMed: 25252795

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