APC Anti-DcR1 antibody [TRAIL-R3-02] (ab243087)
![Flow Cytometry - APC Anti-DcR1 antibody [TRAIL-R3-02] (ab243087)](https://www.abcam.com/ps/products/243/ab243087/Images/ab243087-332393-87j.jpg "Flow Cytometry - APC Anti-DcR1 antibody [TRAIL-R3-02] (ab243087)")
Key features and details
- APC Mouse monoclonal [TRAIL-R3-02] to DcR1
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG1
Overview
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Product name
APC Anti-DcR1 antibody [TRAIL-R3-02]
See all DcR1 primary antibodies -
Description
APC Mouse monoclonal [TRAIL-R3-02] to DcR1 -
Host species
Mouse -
Conjugation
APC. Ex: 645nm, Em: 660nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Fusion protein corresponding to Human DcR1. hIgGhc fusion protein
Database link: O14798 -
Positive control
- Flow Cyt: HEK-293 cells transfected with DcR1.
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General notes
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Store In the Dark. -
Storage buffer
pH: 7.4
Preservative: 0.0975% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Size exclusion -
Purification notes
The purified antibody is conjugated with cross-linked Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography. -
Clonality
Monoclonal -
Clone number
TRAIL-R3-02 -
Isotype
IgG1 -
Research areas
Associated products
Applications
Our Abpromise guarantee covers the use of ab243087 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | Use a concentration of 1 µg/ml. |
Target
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Relevance
DcR1 / TRAIL-R3 / TRID / LIT is one of the two putative decoy receptors identified for TRAIL, one of the members of TNF family of apoptosis inducing proteins. The other putative decoy receptor is called DcR2 / TRUNDD / TRAIL-R4. DcR1 is attached to the cell surface through glycophospholipid anchor. It has the extracellular TRAIL binding domain but lacks the cytoplasmic domain to induce apoptotic signal. Hence overexpression of DcR1 inhibits the TRAIL induced apoptosis. -
Cellular localization
Cell Membrane and Cytoplasmic -
Database links
- Entrez Gene: 8794 Human
- Omim: 603613 Human
- SwissProt: O14798 Human
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Alternative names
- Antagonist decoy receptor for TRAIL/Apo 2L antibody
- CD263 antibody
- Cytotoxic TRAIL receptor 3 antibody
see all
Images
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Flow Cytometry - APC Anti-DcR1 antibody [TRAIL-R3-02] (ab243087)
Flow Cytometric analysis of HEK-293 (Human epithelial cell line from embryonic kidney) cells transfected with DcR1 staining DcR1 using ab243087. Surface staining.
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
References (0)
ab243087 has not yet been referenced specifically in any publications.
