APC Anti-FOXP3 antibody [3G3] (ab200568)
![Flow Cytometry (Intracellular) - APC Anti-FOXP3 antibody [3G3] (ab200568)](https://www.abcam.com/ps/products/200/ab200568/Images/ab200568-455294-apc-anti-foxp3-antibody-3g3-flow-cytometry-intracellular-peripheral-blood-human.jpg "Flow Cytometry (Intracellular) - APC Anti-FOXP3 antibody [3G3] (ab200568)")
Key features and details
- APC Mouse monoclonal [3G3] to FOXP3
- Suitable for: Flow Cyt (Intra)
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG1
Overview
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Product name
APC Anti-FOXP3 antibody [3G3]
See all FOXP3 primary antibodies -
Description
APC Mouse monoclonal [3G3] to FOXP3 -
Host species
Mouse -
Conjugation
APC. Ex: 645nm, Em: 660nm -
Tested applications
Suitable for: Flow Cyt (Intra)more details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant full length protein (His-tag) corresponding to Mouse FOXP3 aa 1 to the C-terminus.
Database link: Q99JB6 -
Epitope
The mouse monoclonal antibody 3G3 recognizes the N-terminal region of FOXP3. -
Positive control
- Flow Cyt (Intra): Human peripheral blood.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
Storage buffer
pH: 7.40
Preservative: 0.098% Sodium azide
Constituent: 99% PBS -
Concentration information loading... -
Purity
Size exclusion -
Purification notes
ab200568 is conjugated with Allophycocyanin (APC) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use. -
Clonality
Monoclonal -
Clone number
3G3 -
Isotype
IgG1 -
Research areas
Associated products
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Alternative Versions
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab200568 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt (Intra) |
Use a concentration of 1 - 2 µg/ml.
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| Notes |
|---|
|
Flow Cyt (Intra)
Use a concentration of 1 - 2 µg/ml. |
Target
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Function
Probable transcription factor. Plays a critical role in the control of immune response. -
Involvement in disease
Defects in FOXP3 are the cause of immunodeficiency polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) [MIM:304790]; also known as X-linked autoimmunity-immunodeficiency syndrome. IPEX is characterized by neonatal onset insulin-dependent diabetes mellitus, infections, secretory diarrhea, trombocytopenia, anemia and eczema. It is usually lethal in infancy. -
Sequence similarities
Contains 1 C2H2-type zinc finger.
Contains 1 fork-head DNA-binding domain. -
Cellular localization
Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 50943 Human
- Omim: 300292 Human
- SwissProt: Q9BZS1 Human
- Unigene: 247700 Human
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Alternative names
- AIID antibody
- DIETER antibody
- Forkhead box P3 antibody
see all
Images
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Flow Cytometry (Intracellular) - APC Anti-FOXP3 antibody [3G3] (ab200568)
Flow Cytometry (Intracellular) analysis of human peripheral blood cells (gated on CD4+ cells) labelingFOXP3 with ab200568 at 2 µg/mL.
Datasheets and documents
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Datasheet download
References (1)
ab200568 has been referenced in 1 publication.
- Wei Y et al. Acacetin ameliorates insulin resistance in obesity mice through regulating Treg/Th17 balance via MiR-23b-3p/NEU1 Axis. BMC Endocr Disord 21:57 (2021). PubMed: 33781239
