Key features and details
- APC Rat monoclonal [YN1/1.7.4] to ICAM1
- Reacts with: Mouse
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG2b
Product nameAPC Anti-ICAM1 antibody [YN1/1.7.4]
See all ICAM1 primary antibodies
DescriptionAPC Rat monoclonal [YN1/1.7.4] to ICAM1
ConjugationAPC. Ex: 645nm, Em: 660nm
Species reactivityReacts with: Mouse
The details of the immunogen for this antibody are not available.
- Flow Cyt: C57BL/6 mouse splenocytes.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
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In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.3
Preservative: 0.1% Sodium azide
Also contains a stabilizing agent.
Concentration information loading...
Light chain typekappa
IHC-Fr: Use at an assay dependent dilution.
IP: Use at an assay dependent dilution.
Inhib: Use at an assay dependent dilution.
WB: Use at an assay dependent dilution. Predicted molecular weight: 58 kDa.
Not yet tested in other applications.
Optimal dilutions/concentrations should be determined by the end user.
FunctionICAM proteins are ligands for the leukocyte adhesion protein LFA-1 (integrin alpha-L/beta-2). During leukocyte trans-endothelial migration, ICAM1 engagement promotes the assembly of endothelial apical cups through ARHGEF26/SGEF and RHOG activation. In case of rhinovirus infection acts as a cellular receptor for the virus.
Sequence similaritiesBelongs to the immunoglobulin superfamily. ICAM family.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.
modificationsMonoubiquitinated, which is promoted by MARCH9 and leads to endocytosis.
- Information by UniProt
- Antigen identified by monoclonal antibody BB2 antibody
- BB 2 antibody
- BB2 antibody
ab87026 has not yet been referenced specifically in any publications.