APC Anti-LIGHT/TNFSF14 antibody [7-3 (7)], prediluted (ab155363)
![Flow Cytometry - APC Anti-LIGHT/TNFSF14 antibody [7-3 (7)], prediluted (ab155363)](https://www.abcam.com/ps/products/155/ab155363/Images/ab155363-162510-anti-light-antibody-7-3-7-prediluted-allophycocyanin-flow-cytometry.jpg "Flow Cytometry - APC Anti-LIGHT/TNFSF14 antibody [7-3 (7)], prediluted (ab155363)")
Key features and details
- APC Mouse monoclonal [7-3 (7)] to LIGHT/TNFSF14, prediluted
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
- Isotype: IgG1
Overview
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Product name
APC Anti-LIGHT/TNFSF14 antibody [7-3 (7)], prediluted
See all LIGHT/TNFSF14 primary antibodies -
Description
APC Mouse monoclonal [7-3 (7)] to LIGHT/TNFSF14, prediluted -
Host species
Mouse -
Conjugation
APC. Ex: 645nm, Em: 660nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
The details of the immunogen for this antibody are not available.
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Positive control
- Normal Human peripheral blood cells.
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General notes
This product was previously labelled as LIGHT
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. -
Storage buffer
pH: 7.20
Preservative: 0.09% Sodium azide
Constituents: 99% PBS, 0.2% BSA -
Concentration information loading... -
Purity
Protein G purified -
Clonality
Monoclonal -
Clone number
7-3 (7) -
Isotype
IgG1 -
Light chain type
kappa -
Research areas
Associated products
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Isotype control
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Recombinant Protein
Applications
Our Abpromise guarantee covers the use of ab155363 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| Flow Cyt | Use 5µl for 106 cells. |
Target
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Function
Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. -
Tissue specificity
Predominantly expressed in the spleen but also found in the brain. Weakly expressed in peripheral lymphoid tissues and in heart, placenta, liver, lung, appendix, and kidney, and no expression seen in fetal tissues, endocrine glands, or nonhematopoietic tumor lines. -
Sequence similarities
Belongs to the tumor necrosis factor family. -
Post-translational
modificationsN-glycosylated.
The soluble form of isoform 1 derives from the membrane form by proteolytic processing. -
Cellular localization
Cytoplasm; Secreted and Cell membrane. - Information by UniProt
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Database links
- Entrez Gene: 8740 Human
- Omim: 604520 Human
- SwissProt: O43557 Human
- Unigene: 129708 Human
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Alternative names
- CD 258 antibody
- CD258 antibody
- CD258 antigen antibody
see all
Images
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Flow Cytometry - APC Anti-LIGHT/TNFSF14 antibody [7-3 (7)], prediluted (ab155363)Flow cytometric analysis of normal Human peripheral blood cells with Anti-Human CD8a PE and mouse IgG1 kappa Isotype Control APC (left) or 5 µl (0.25 µg) of ab155363 (right). Total viable cells were used for analysis.
Datasheets and documents
References (0)
ab155363 has not yet been referenced specifically in any publications.
