Recombinant APC Anti-Prolactin Receptor/PRL-R antibody [204] (ab275715)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- APC Rabbit monoclonal [204] to Prolactin Receptor/PRL-R
- Suitable for: Flow Cyt
- Reacts with: Human
- Conjugation: APC. Ex: 645nm, Em: 660nm
Overview
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Product name
APC Anti-Prolactin Receptor/PRL-R antibody [204]
See all Prolactin Receptor/PRL-R primary antibodies -
Description
APC Rabbit monoclonal [204] to Prolactin Receptor/PRL-R -
Host species
Rabbit -
Conjugation
APC. Ex: 645nm, Em: 660nm -
Tested applications
Suitable for: Flow Cytmore details -
Species reactivity
Reacts with: Human -
Immunogen
Recombinant fragment (His-tag) corresponding to Human Prolactin Receptor/PRL-R aa 1-250 (extracellular).
Database link: P16471 -
Positive control
- Flow Cyt: MCF-7 cells
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Do Not Freeze. Store In the Dark. -
Storage buffer
Preservative: 0.09% Sodium azide
Constituent: 0.5% BSA -
Concentration information loading...
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Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
204 -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab275715 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt |
Use at an assay dependent concentration.
10 µL/Test |
Notes |
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Flow Cyt
Use at an assay dependent concentration. 10 µL/Test |
Target
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Function
This is a receptor for the anterior pituitary hormone prolactin (PRL). Isoform 4 is unable to transduce prolactin signaling. Isoform 6 is unable to transduce prolactin signaling. -
Tissue specificity
Expressed in breast, placenta, kidney, liver and pancreas. -
Sequence similarities
Belongs to the type I cytokine receptor family. Type 1 subfamily.
Contains 2 fibronectin type-III domains. -
Domain
The WSXWS motif appears to be necessary for proper protein folding and thereby efficient intracellular transport and cell-surface receptor binding.
The box 1 motif is required for JAK interaction and/or activation. -
Cellular localization
Secreted and Membrane. - Information by UniProt
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Database links
- Entrez Gene: 5618 Human
- Omim: 176761 Human
- SwissProt: P16471 Human
- Unigene: 368587 Human
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Alternative names
- AI987712 antibody
- CLONE SPM213 antibody
- CPRLP antibody
see all
Images
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
Datasheets and documents
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Datasheet download
References (0)
ab275715 has not yet been referenced specifically in any publications.