Key features and details
- Rabbit polyclonal to Apc4
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-Apc4 antibody
See all Apc4 primary antibodies
DescriptionRabbit polyclonal to Apc4
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Rat
Synthetic peptide conjugated to KLH, corresponding to N terminal region of Human Apc4.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferPreservative: 0.02% Sodium azide
Constituent: 99% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab113364 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 92 kDa.|
|IHC-P||Use a concentration of 5 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionComponent of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
PathwayProtein modification; protein ubiquitination.
Sequence similaritiesBelongs to the APC4 family.
- Information by UniProt
- ANAPC 4 antibody
- anapc4 antibody
- Anaphase Promoting Complex Subunit 4 antibody
ab113364, at 5µg/ml, staining Apc4 in Formalin-fixed, Paraffin-embedded Human Spleen tissue by Immunohistochemistry.
ab113364, at 5µg/ml, staining Apc4 in Formalin-fixed, Paraffin-embedded Human uterus tissue by Immunohistochemistry.
Lane 1 : Anti-Apc4 antibody (ab113364) at 1 µg/ml
Lane 2 : Anti-Apc4 antibody (ab113364) at 2 µg/ml
All lanes : Mouse liver tissue lysate
Predicted band size: 92 kDa
ab113364 has not yet been referenced specifically in any publications.