Key features and details
- Rabbit polyclonal to Apc5
- Suitable for: ICC/IF, WB, IHC-P
- Reacts with: Mouse, Rat, Human
- Isotype: IgG
Product nameAnti-Apc5 antibody
See all Apc5 primary antibodies
DescriptionRabbit polyclonal to Apc5
Specificityab106487 is predicted not to cross-react with other APC family members.
Tested applicationsSuitable for: ICC/IF, WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Rat, Human
A 17 amino acid synthetic peptide near the center of Human Apc5 (UniProt Q9UJX4).
- Human kidney tissue lysate; Rat kidney tissue
Storage instructionsShipped at 4°C. Store at 4°C (stable for up to 12 months).
Storage bufferPreservative: 0.02% Sodium azide
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab106487 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|ICC/IF||Use a concentration of 20 µg/ml.|
|WB||Use a concentration of 1 - 2 µg/ml. Predicted molecular weight: 85 kDa.|
|IHC-P||Use at an assay dependent concentration.|
FunctionComponent of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
PathwayProtein modification; protein ubiquitination.
Sequence similaritiesBelongs to the APC5 family.
Contains 4 TPR repeats.
- Information by UniProt
- 2510006G12Rik antibody
- AA408751 antibody
- AA536819 antibody
Lane 1 : Anti-Apc5 antibody (ab106487) at 1 µg/ml
Lane 2 : Anti-Apc5 antibody (ab106487) at 2 µg/ml
All lanes : Human kidney tissue lysate
Lysates/proteins at 15 µg per lane.
Predicted band size: 85 kDa
Immunofluorescence of Apc5 in rat kidney tissue with ab106487 at 20 ug/mL.
ab106487, at 5 µg/ml, staining Apc5 in Rat kidney tissue by Immunohistochemistry.
ab106487 has not yet been referenced specifically in any publications.