Key features and details
- APC/Cy7® Mouse monoclonal [WM53] to CD33
- Suitable for: Flow Cyt
- Reacts with: Human, Non human primates
- Conjugation: APC/Cy7®. Ex: 650nm, Em: 774nm
- Isotype: IgG1
Related conjugates and formulations
Product nameAPC/Cy7® Anti-CD33 antibody [WM53]
See all CD33 primary antibodies
DescriptionAPC/Cy7® Mouse monoclonal [WM53] to CD33
ConjugationAPC/Cy7®. Ex: 650nm, Em: 774nm
Tested applicationsSuitable for: Flow Cytmore details
Species reactivityReacts with: Human, Non human primates
Tissue, cells or virus corresponding to Human CD33. Human AML cells.
- Human blood cells.
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Storage instructionsShipped at 4°C. Store at +4°C. Store In the Dark.
Storage bufferpH: 7.4
Preservative: 0.0975% Sodium azide
Constituents: 0.2% BSA, 99% PBS
Concentration information loading...
- APC Anti-CD33 antibody [WM53] (ab118967)
- PerCP Anti-CD33 antibody [WM53] (ab124531)
- Anti-CD33 antibody [WM53] - BSA and Azide free (ab213050)
- PE/Cy5® Anti-CD33 antibody [WM53] (ab233448)
- PE Anti-CD33 antibody [WM53] (ab233577)
- FITC Anti-CD33 antibody [WM53] (ab234216)
- PE/Cy7® Anti-CD33 antibody [WM53] (ab239310)
- Anti-CD33 antibody [WM53] - BSA and Azide free (ab252263)
- Alexa Fluor® 700 Anti-CD33 antibody [WM53] (ab269306)
- Anti-CD33 antibody [WM53] (ab30371)
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab206634 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use 4µl for 106 cells.
Use 4µl for 106 cells.
FunctionPutative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Tissue specificityMonocytic/myeloid lineage cells.
Sequence similaritiesBelongs to the immunoglobulin superfamily. SIGLEC (sialic acid binding Ig-like lectin) family.
Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
Contains 1 Ig-like V-type (immunoglobulin-like) domain.
DomainContains 2 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phosphorylated ITIM motif can bind the SH2 domain of several SH2-containing phosphatases.
modificationsPhosphorylation of Tyr-340 is involved in binding to PTPN6 and PTPN11. Phosphorylation of Tyr-358 is involved in binding to PTPN6.
Cellular localizationCell membrane.
- Information by UniProt
- CD 33 antibody
- CD33 antibody
- CD33 antigen (gp67) antibody
ab206634 has not yet been referenced specifically in any publications.