Key features and details
- APC/Cy7® Rat monoclonal [DX5] to Integrin alpha 2
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: APC/Cy7®. Ex: 650nm, Em: 774nm
- Isotype: IgM
Product nameAPC/Cy7® Anti-Integrin alpha 2 antibody [DX5]
See all Integrin alpha 2 primary antibodies
DescriptionAPC/Cy7® Rat monoclonal [DX5] to Integrin alpha 2
ConjugationAPC/Cy7®. Ex: 650nm, Em: 774nm
Specificityab46795 reacts with mouse CD49b, Mr 160-kDa.
Tested applicationsSuitable for: Flow Cytmore details
Unsuitable for: IHC-Fr or IHC-P
Species reactivityReacts with: Mouse
RIL 2 propagated NK1.1+ cells from C57BL/6 mice. (Fusion Partner Mouse SP2/0 myeloma cell line).
General notesThis product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5,268,486 and related patents. Cy and CyDye are trademarks of GE Healthcare Limited.
Reproducibility is key to advancing scientific discovery and accelerating scientists’ next breakthrough.
Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
Please check that this product meets your needs before purchasing. If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, as well as customer reviews and Q&As.
Storage instructionsShipped at 4°C. Store at +4°C.
Storage bufferpH: 7.1
Preservative: 0.09% Sodium azide
Constituents: PBS, 16% Sucrose
Also contains stabilising agent.
Concentration information loading...
Light chain typekappa
Our Abpromise guarantee covers the use of ab46795 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|Flow Cyt||Use 0.2µl for 106 cells.|
FunctionIntegrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.
Sequence similaritiesBelongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain.
DomainThe integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage.
- Information by UniProt
- BR antibody
- CD 49b antibody
- CD49 antigen like family member B antibody
ab46795 has not yet been referenced specifically in any publications.