APC/Cy7® Anti-Integrin alpha 2 antibody [DX5] (ab46795)
Key features and details
- APC/Cy7® Rat monoclonal [DX5] to Integrin alpha 2
- Suitable for: Flow Cyt
- Reacts with: Mouse
- Conjugation: APC/Cy7®. Ex: 650nm, Em: 774nm
- Isotype: IgM
Overview
-
Product name
APC/Cy7® Anti-Integrin alpha 2 antibody [DX5]
See all Integrin alpha 2 primary antibodies -
Description
APC/Cy7® Rat monoclonal [DX5] to Integrin alpha 2 -
Host species
Rat -
Conjugation
APC/Cy7®. Ex: 650nm, Em: 774nm -
Specificity
ab46795 reacts with mouse CD49b, Mr 160-kDa. -
Tested applications
Suitable for: Flow Cytmore details
Unsuitable for: IHC-Fr or IHC-P -
Species reactivity
Reacts with: Mouse -
Immunogen
Tissue, cells or virus corresponding to Mouse Integrin alpha 2. NK cells isolated from C57BL/6 mice
-
General notes
This product or portions thereof is manufactured under license from Carnegie Mellon University under U.S. Patent Number 5, 268, 486 and related patents. Cy® and CyDye® are trademarks of Cytiva.
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C. Store In the Dark. -
Storage buffer
pH: 7.1
Preservative: 0.09% Sodium azide
Constituents: PBS, 16% Sucrose
Also contains stabilising agent. -
Concentration information loading...
-
Purity
Purified IgM -
Clonality
Monoclonal -
Clone number
DX5 -
Isotype
IgM -
Light chain type
kappa -
Research areas
Associated products
-
Alternative Versions
-
Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab46795 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
Flow Cyt | (1) |
Use 0.2µl for 106 cells.
|
Notes |
---|
Flow Cyt
Use 0.2µl for 106 cells. |
Target
-
Function
Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. -
Sequence similarities
Belongs to the integrin alpha chain family.
Contains 7 FG-GAP repeats.
Contains 1 VWFA domain. -
Domain
The integrin I-domain (insert) is a VWFA domain. Integrins with I-domains do not undergo protease cleavage. -
Cellular localization
Membrane. - Information by UniProt
-
Database links
- Entrez Gene: 16398 Mouse
- SwissProt: Q62469 Mouse
- Unigene: 5007 Mouse
-
Alternative names
- BR antibody
- CD 49b antibody
- CD49 antigen like family member B antibody
see all
Images
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab46795 has not yet been referenced specifically in any publications.