Product nameAnti-APEG1 antibody
DescriptionRabbit polyclonal to APEG1
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
- APEG1 transfected 293T cell lysate.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term.
Storage bufferpH: 7.20
Constituent: 99% PBS
Concentration information loading...
PurityProtein A purified
Our Abpromise guarantee covers the use of ab168746 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 354 kDa.|
FunctionIsoform 3 may have a role in regulating the growth and differentiation of arterial smooth muscle cells.
Tissue specificityIsoform 1 is preferentially expressed in striated muscle. Non-kinase form such as isoform 3 is predominantly expressed in the aorta. Isoform 3 appears to be expressed only in highly differentiated ASMC in normal vessel walls and down-regulated in dedifferentiated ASMC in vivo. In response to vascular injuries ASMC dedifferentiate and change from a quiescent and contractile phenotype to a proliferative and synthetic phenotype. This proliferation of vascular smooth muscle cells is one of the most prominent features of atherosclerosis.
Sequence similaritiesBelongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
Contains 2 fibronectin type-III domains.
Contains 9 Ig-like (immunoglobulin-like) domains.
Contains 2 protein kinase domains.
modificationsMay be autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR.
- Information by UniProt
- APEG1 antibody
- Aortic preferentially expressed gene 1 antibody
- Aortic preferentially expressed protein 1 antibody
All lanes : Anti-APEG1 antibody (ab168746) at 1 µg/ml
Lane 1 : APEG1 transfected 293T cell lysate (12.70 KDa)
Lane 2 : Non-transfected 293T cell lysate
Lysates/proteins at 15 µl per lane.
All lanes : Goat Anti-Rabbit IgG (H+L), Peroxidase Conjugated secondary antibody at 1/7500 dilution
Predicted band size: 354 kDa
ab168746 has not yet been referenced specifically in any publications.