Overview

  • Product name

    Apelin 36 (human), Endogenous apelin receptor (APJ) agonist
  • Description

    Endogenous apelin receptor (APJ) agonist
  • Biological description

    Endogenous apelin receptor (APJ) agonist (EC50 = 20 nM). Exhibits cardioprotective effect and inhibits entry of HIV-1 and HIV-2 into NP-2/CD4 cells. Active in vivo.
  • CAS Number

    252642-12-9
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Simpkin JC  et al. Apelin-13 and apelin-36 exhibit direct cardioprotective activity against ischemia-reperfusion injury. Basic Res Cardiol 102:518-28 (2007). Read more (PubMed: 17694254) »
  • Zou MX  et al. Apelin peptides block the entry of human immunodeficiency virus (HIV). FEBS Lett 473:15-8 (2000). Read more (PubMed: 10802050) »
  • Tatemoto K  et al. Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem Biophys Res Commun 251:471-6 (1998). Read more (PubMed: 9792798) »

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