Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPNCIR158] to Apelin
- Suitable for: ELISA
- Reacts with: Human
Product nameAnti-Apelin antibody [EPNCIR158]
See all Apelin primary antibodies
SpecificityApelin is a precursor protein that is cleaved into several different chains. Anti-Salcut-NH2 is one very specific form. ab151565 recognizes Apelin "salcut-NH2" amidated peptide (16 mer).
Species reactivityReacts with: Human
Synthetic peptide corresponding to Human Apelin.
This antibody was developed as part of a collaboration between Epitomics, the National Cancer Institute's Center for Cancer Research and the lab of Frank F Cuttitta. View antibodies from NCI Center for Cancer Research Collaboration.
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
We are constantly working hard to ensure we provide our customers with best in class antibodies. As a result of this work we are pleased to now offer this antibody in purified format. We are in the process of updating our datasheets. The purified format is designated 'PUR' on our product labels. If you have any questions regarding this update, please contact our Scientific Support team.
Storage instructionsShipped at 4°C. Store at -20ºC.
Storage bufferPreservative: 0.01% Sodium azide
Constituents: 59% PBS, 40% Glycerol, 0.5% BSA
Concentration information loading...
PurityProtein A purified
|ELISA||1/5000 - 1/10000.|
FunctionEndogenous ligand for APJ, an alternative coreceptor with CD4 for HIV-1 infection. Inhibits HIV-1 entry in cells coexpressing CD4 and APJ. Apelin-36 has a greater inhibitory activity on HIV infection than other synthetic apelin derivatives. The oral intake in the colostrum and the milk could have a role in the modulation of the immune responses in neonates. May also have a role in the central control of body fluid homeostasis by influencing AVP release and drinking behavior.
Tissue specificityExpressed in the brain with highest levels in the frontal cortex, thalamus, hypothalamus and midbrain. Secreted by the mammary gland into the colostrum and the milk.
Sequence similaritiesBelongs to the apelin family.
modificationsSeveral active peptides may be produced by proteolytic processing of the peptide precursor.
- Information by UniProt
- AGTRL1 ligand antibody
- APEL antibody
- APEL_HUMAN antibody
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
ab151565 has not yet been referenced specifically in any publications.