Validated using a knockout cell line

Anti-APG5L/ATG5 antibody [EPR1755(2)] (ab108327)

Publishing research using ab108327? Please let us know so that we can cite the reference in this datasheet.

ab108327 has been referenced in 31 publications.

  • Wang W  et al. SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition. J Exp Clin Cancer Res 37:37 (2018). WB ; Human . PubMed: 29475441
  • Yu X  et al. d-limonene exhibits antitumor activity by inducing autophagy and apoptosis in lung cancer. Onco Targets Ther 11:1833-1847 (2018). PubMed: 29670359
  • Deshpande S  et al. Reduced Autophagy by a microRNA-mediated Signaling Cascade in Diabetes-induced Renal Glomerular Hypertrophy. Sci Rep 8:6954 (2018). PubMed: 29725042
  • Perot BP  et al. Autophagy diminishes the early interferon-ß response to influenza A virus resulting in differential expression of interferon-stimulated genes. Cell Death Dis 9:539 (2018). PubMed: 29748576
  • Parodi C  et al. Autophagy is essential for maintaining the growth of a human (mini-)organ: Evidence from scalp hair follicle organ culture. PLoS Biol 16:e2002864 (2018). ICC/IF ; Human . PubMed: 29590104
  • Du J  et al. Andrographolide protects mouse astrocytes against hypoxia injury by promoting autophagy and S100B expression. Braz J Med Biol Res 51:e7061 (2018). PubMed: 29694508
  • Liu J  et al. BECN1-dependent CASP2 incomplete autophagy induction by binding to rabies virus phosphoprotein. Autophagy 13:739-753 (2017). PubMed: 28129024
  • Zhang Y  et al. JNK pathway mediates curcumin-induced apoptosis and autophagy in osteosarcoma MG63 cells. Exp Ther Med 14:593-599 (2017). WB . PubMed: 28672972
  • Li YY  et al. Thioredoxin-2 protects against oxygen-glucose deprivation/reperfusion injury by inhibiting autophagy and apoptosis in H9c2 cardiomyocytes. Am J Transl Res 9:1471-1482 (2017). PubMed: 28386372
  • Mantegazza AR  et al. Increased autophagic sequestration in adaptor protein-3 deficient dendritic cells limits inflammasome activity and impairs antibacterial immunity. PLoS Pathog 13:e1006785 (2017). PubMed: 29253868
  • Gan L  et al. Reduced Endoplasmic Reticulum Stress-Mediated Autophagy Is Required for Leptin Alleviating Inflammation in Adipose Tissue. Front Immunol 8:1507 (2017). PubMed: 29250056
  • Zhang HH  et al. Role of 5-Aza-CdR in mitomycin-C chemosensitivity of T24 bladder cancer cells. Oncol Lett 14:5652-5656 (2017). PubMed: 29142609
  • Qiao L  et al. Ginsenoside Rb1 Enhances Atherosclerotic Plaque Stability by Improving Autophagy and Lipid Metabolism in Macrophage Foam Cells. Front Pharmacol 8:727 (2017). PubMed: 29114222
  • Yang C  et al. A Yin-Yang 1/miR-30a regulatory circuit modulates autophagy in pancreatic cancer cells. J Transl Med 15:211 (2017). PubMed: 29052509
  • Wang Y  et al. Infectious Bursal Disease Virus Subverts Autophagic Vacuoles To Promote Viral Maturation and Release. J Virol 91:N/A (2017). PubMed: 27974565
  • Kemp V  et al. Oncolytic Reovirus Infection Is Facilitated by the Autophagic Machinery. Viruses 9:N/A (2017). PubMed: 28934149
  • Tang Y  et al. Protective effect of autophagy on endoplasmic reticulum stress induced apoptosis of alveolar epithelial cells in rat models of COPD. Biosci Rep 37:N/A (2017). PubMed: 28963374
  • Gómez-Puerto MC  et al. Autophagy proteins ATG5 and ATG7 are essential for the maintenance of human CD34(+) hematopoietic stem-progenitor cells. Stem Cells N/A:N/A (2016). PubMed: 26930546
  • Chen Y  et al. FGFR antagonist induces protective autophagy in FGFR1-amplified breast cancer cell. Biochem Biophys Res Commun N/A:N/A (2016). WB ; Human . PubMed: 26993162
  • Wu Y  et al. Targeting the MIR34C-5p-ATG4B-autophagy axis enhances the sensitivity of cervical cancer cells to pirarubicin. Autophagy N/A:0 (2016). PubMed: 27097054
  • Lee JP  et al. Loss of autophagy enhances MIF/macrophage migration inhibitory factor release by macrophages. Autophagy N/A:1-10 (2016). PubMed: 27163877
  • Xue H  et al. A Novel Tumor-promoting Mechanism of IL6 and the Therapeutic Efficacy of Tocilizumab: Hypoxia-induced IL6 Is a Potent Autophagy Initiator in Glioblastoma via the p-STAT3-MIR155-3p-CREBRF Pathway. Autophagy N/A:0 (2016). WB ; Human . PubMed: 27163161
  • Livingston MJ  et al. Persistent activation of autophagy in kidney tubular cells promotes renal interstitial fibrosis during unilateral ureteral obstruction. Autophagy 12:976-98 (2016). PubMed: 27123926
  • Dong Q  et al. Tetrahydroxystilbene Glucoside Inhibits Excessive Autophagy and Improves Microvascular Endothelial Dysfunction in Prehypertensive Spontaneously Hypertensive Rats. Am J Chin Med 44:1393-1412 (2016). Rat . PubMed: 27776426
  • García-Fernández M  et al. Metastatic risk and resistance to BRAF inhibitors in melanoma defined by selective allelic loss of ATG5. Autophagy 12:1776-1790 (2016). PubMed: 27464255
  • Goodall ML  et al. The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis. Dev Cell 37:337-49 (2016). PubMed: 27219062
  • Sun H  et al. Resistance of glioma cells to nutrient-deprived microenvironment can be enhanced by CD133-mediated autophagy. Oncotarget 7:76238-76249 (2016). WB ; Rat . PubMed: 27780926
  • Huang M  et al. Autophagy mediates proteolysis of NPM1 and HEXIM1 and sensitivity to BET inhibition in AML cells. Oncotarget 7:74917-74930 (2016). WB ; Human . PubMed: 27732946
  • Tan S  et al. Enhancement of oxaliplatin-induced cell apoptosis and tumor suppression by 3-methyladenine in colon cancer. Oncol Lett 9:2056-2062 (2015). WB ; Mouse . PubMed: 26137012
  • Vlahava VM  et al. CD40 ligand exhibits a direct antiviral effect on Herpes Simplex Virus type-1 infection via a PI3K-dependent, autophagy-independent mechanism. Cell Signal 27:1253-63 (2015). PubMed: 25765994
  • Xie M  et al. Histone deacetylase inhibition blunts ischemia/reperfusion injury by inducing cardiomyocyte autophagy. Circulation 129:1139-51 (2014). PubMed: 24396039


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