Aphidicolin, DNA polymerase alpha, delta and epsilon inhibitor (ab142400)

Overview

  • Product name

    Aphidicolin, DNA polymerase alpha, delta and epsilon inhibitor
  • Description

    DNA polymerase α, δ and ε inhibitor
  • Biological description

    DNA polymerase α, δ and ε inhibitor. Tetracyclic diterpene antibiotic. Reversible inhibitor of eukaryotic nuclear DNA replication. It blocks the cell cycle at early S phase.
  • Purity

    > 98%
  • CAS Number

    38966-21-1
  • Chemical structure

    Chemical Structure

Properties

References

This product has been referenced in:

  • Zhang TY  et al. Positive effects of treatment of donor cells with aphidicolin on the preimplantation development of somatic cell nuclear transfer embryos in Chinese Bama mini-pig (Sus Scrofa). Anim Sci J 83:103-10 (2012). Read more (PubMed: 22339690) »
  • Recolin B & Maiorano D Implication of RPA32 phosphorylation in S-phase checkpoint signalling at replication forks stalled with aphidicolin in Xenopus egg extracts. Biochem Biophys Res Commun 427:785-9 (2012). Read more (PubMed: 23047005) »
  • Nicodemo D  et al. Chromosomal expression and localization of aphidicolin-induced fragile sites in the standard karyotype of river buffalo (Bubalus bubalis). Cytogenet Genome Res 120:178-82 (2008). Read more (PubMed: 18467845) »
See all 2 Publications for this product

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