Overview

  • Product name

    Apigenin, Anticancer agent
  • Description

    Anticancer agent
  • Biological description

    Plant flavone. Antioxidant, anti-inflammatory and anticancer properties. Effects a wide range of molecular targets including caspases, fatty acid synthase, topoisomerase and nuclear factor-κB.
  • Purity

    > 98%
  • CAS Number

    520-36-5
  • Chemical structure

    Chemical Structure

Properties

Images

  • (A-D). The release of cytokines as assessed using Human Cytokine Array C1000 membranes from MDA-MB-231 cells ± TNFα ± Apigenin. [A] Ctrls, [B] TNFα-treated (40ng/mL) [C] Apigenin (40μM) and [D] TNFα-treated (40ng/mL) + Apigenin (40μM) co-treated cells.

References

This product has been referenced in:

  • Patel D  et al. Apigenin and cancer chemoprevention: progress, potential and promise (review). Int J Oncol 30:233-45 (2007). Read more (PubMed: 17143534) »
  • Shukla S & Gupta S Molecular targets for apigenin-induced cell cycle arrest and apoptosis in prostate cancer cell xenograft. Mol Cancer Ther 5:843-52 (2006). Read more (PubMed: 16648554) »
  • Lin JK  et al. Suppression of protein kinase C and nuclear oncogene expression as possible molecular mechanisms of cancer chemoprevention by apigenin and curcumin. J Cell Biochem Suppl 28-29:39-48 (1997). Read more (PubMed: 9589348) »
See 1 Publication for this product

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