Overview

  • Product name

    Anti-APIP antibody
  • Description

    Rabbit polyclonal to APIP
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Cow
  • Immunogen

    Recombinant fragment, corresponding to a region within amino acids 1-242 of Human APIP (Uniprot ID: Q96GX9).

  • Positive control

    • 293T, A431, H1299, HeLa, HepG2, Molt4, Raji whole cell lysate

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.00
    Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab154258 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/3000. Predicted molecular weight: 27 kDa.

Target

  • Function

    Catalyzes the dehydration of methylthioribulose-1-phosphate (MTRu-1-P) into 2,3-diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P). Has an anti-apoptotic function and prevents muscle ischemic damage. Inhibits the cytochrome c-dependent and APAF1-mediated cell death.
  • Tissue specificity

    Ubiquitously expressed with high expression in skeletal muscle, heart and kidney.
  • Pathway

    Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.
  • Sequence similarities

    Belongs to the aldolase class II family. MtnB subfamily.
  • Cellular localization

    Cytoplasm.
  • Information by UniProt
  • Database links

  • Alternative names

    • Apaf1 Interacting Protein antibody
    • APAF1-interacting protein antibody
    • APIP antibody
    • APIP2 antibody
    • CG129 antibody
    • CGI 29 antibody
    • CGI29 antibody
    • dJ179L10.2 antibody
    • MMRP19 antibody
    • Monocyte/macrophage protein 19 antibody
    • MTNB_HUMAN antibody
    • MTRu 1 P dehydratase antibody
    • MTRu-1-P dehydratase antibody
    • Probable methylthioribulose 1 phosphate dehydratase antibody
    • Probable methylthioribulose-1-phosphate dehydratase antibody
    see all

Images

  • All lanes : Anti-APIP antibody (ab154258) at 1/1000 dilution

    Lane 1 : MOLT4 whole cell lysate
    Lane 2 : Raji whole cell lysate

    Lysates/proteins at 30 µg per lane.

    Predicted band size: 27 kDa



    12% SDS PAGE

References

ab154258 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab154258.
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