Anti-APLP2 antibody (ab137597)
Key features and details
- Rabbit polyclonal to APLP2
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Get better batch-to-batch reproducibility with a recombinant antibody
- Research with confidence – consistent and reproducible results with every batch
- Long-term and scalable supply – powered by recombinant technology for fast production
- Success from the first experiment – confirmed specificity through extensive validation
- Ethical standards compliant – production is animal-free
Overview
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Product name
Anti-APLP2 antibody
See all APLP2 primary antibodies -
Description
Rabbit polyclonal to APLP2 -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human
Predicted to work with: Chimpanzee -
Immunogen
Recombinant fragment, corresponding to a region within N terminal amino acids 17-235 of Human APLP2.
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Positive control
- WB: Human HEK-293T, A431, HeLa, HepG2 and A-375 cell lysates; Mouse brain lysate. IHC-P: Mouse liver and fore brain tissue.
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine) -
Concentration information loading...
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Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab137597 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
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WB |
1/1000. Predicted molecular weight: 87 kDa.
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IHC-P |
1/100 - 1/1000.
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Notes |
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WB
1/1000. Predicted molecular weight: 87 kDa. |
IHC-P
1/100 - 1/1000. |
Target
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Function
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. -
Tissue specificity
Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues. -
Sequence similarities
Belongs to the APP family.
Contains 1 BPTI/Kunitz inhibitor domain. -
Post-translational
modificationsThe BPTI/Kunitz inhibitor domain is O-glycosylated. -
Cellular localization
Cell membrane. Nucleus. - Information by UniProt
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Database links
- Entrez Gene: 334 Human
- Entrez Gene: 11804 Mouse
- Omim: 104776 Human
- SwissProt: Q06481 Human
- SwissProt: Q06335 Mouse
- Unigene: 370247 Human
- Unigene: 19133 Mouse
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Alternative names
- amyloid beta (A4) precursor like protein 2 antibody
- Amyloid like protein 2 antibody
- Amyloid precursor protein homolog HSD 2 antibody
see all
Images
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Paraffin-embedded mouse liver tissue stained for APLP2 using ab137597 at 1/500 dilution in immunohistochemical analysis.
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Paraffin-embedded mouse fore brain tissue stained for APLP2 using ab137597 at 1/500 dilution in immunohistochemical analysis.
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All lanes : Anti-APLP2 antibody (ab137597) at 1/1000 dilution
Lane 1 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
Lane 2 : A431 (human epidermoid carcinoma cell line) whole cell lysate
Lane 3 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
Lane 4 : HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate
Lane 5 : A-375 (human malignant melanoma cell line) whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 87 kDa -
Anti-APLP2 antibody (ab137597) at 1/1000 dilution + Mouse brain lysate at 50 µg
Predicted band size: 87 kDa
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab137597 has not yet been referenced specifically in any publications.