Key features and details
- Rabbit polyclonal to APLP2
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Product nameAnti-APLP2 antibody
See all APLP2 primary antibodies
DescriptionRabbit polyclonal to APLP2
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Mouse, Human
Predicted to work with: Chimpanzee
Recombinant fragment, corresponding to a region within N terminal amino acids 17-235 of Human APLP2.
- WB: Human HEK-293T, A431, HeLa, HepG2 and A-375 cell lysates; Mouse brain lysate. IHC-P: Mouse liver and fore brain tissue.
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Abcam is leading the way with our range of recombinant antibodies, knockout-validated antibodies and knockout cell lines, all of which support improved reproducibility.
We are also planning to innovate the way in which we present recommended applications and species on our product datasheets, so that only applications & species that have been tested in our own labs, our suppliers or by selected trusted collaborators are covered by our Abpromise™ guarantee.
In preparation for this, we have started to update the applications & species that this product is Abpromise guaranteed for.
We are also updating the applications & species that this product has been “predicted to work with,” however this information is not covered by our Abpromise guarantee.
Applications & species from publications and Abreviews that have not been tested in our own labs or in those of our suppliers are not covered by the Abpromise guarantee.
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Storage bufferpH: 7.00
Preservative: 0.025% Proclin 300
Constituents: 78% PBS, 1% BSA, 20% Glycerol (glycerin, glycerine)
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab137597 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/1000. Predicted molecular weight: 87 kDa.|
|IHC-P||1/100 - 1/1000.|
FunctionMay play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Tissue specificityExpressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
Sequence similaritiesBelongs to the APP family.
Contains 1 BPTI/Kunitz inhibitor domain.
modificationsThe BPTI/Kunitz inhibitor domain is O-glycosylated.
Cellular localizationCell membrane. Nucleus.
- Information by UniProt
- amyloid beta (A4) precursor like protein 2 antibody
- Amyloid like protein 2 antibody
- Amyloid precursor protein homolog HSD 2 antibody
Paraffin-embedded mouse liver tissue stained for APLP2 using ab137597 at 1/500 dilution in immunohistochemical analysis.
Paraffin-embedded mouse fore brain tissue stained for APLP2 using ab137597 at 1/500 dilution in immunohistochemical analysis.
All lanes : Anti-APLP2 antibody (ab137597) at 1/1000 dilution
Lane 1 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) whole cell lysate
Lane 2 : A431 (human epidermoid carcinoma cell line) whole cell lysate
Lane 3 : HeLa (human epithelial cell line from cervix adenocarcinoma) whole cell lysate
Lane 4 : HepG2 (human liver hepatocellular carcinoma cell line) whole cell lysate
Lane 5 : A-375 (human malignant melanoma cell line) whole cell lysate
Lysates/proteins at 30 µg per lane.
Predicted band size: 87 kDa
Anti-APLP2 antibody (ab137597) at 1/1000 dilution + Mouse brain lysate at 50 µg
Predicted band size: 87 kDa
ab137597 has not yet been referenced specifically in any publications.