Overview

  • Product name

    Anti-APLP2 antibody - C-terminal
    See all APLP2 primary antibodies
  • Description

    Rabbit polyclonal to APLP2 - C-terminal
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Rat, Human
    Predicted to work with: Mouse
  • Immunogen

    Synthetic peptide corresponding to Human APLP2 aa 639-656 (C terminal).
    Sequence:

    EEKVINSKNKVDENMVID


    Database link: Q06481

  • Positive control

    • Rat brain and heart tissue lysates; SMMC cell lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab190925 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 87 kDa.

The detection limit for APLP2 is approximately 0.5ng/lane under reducing conditions.

Target

  • Function

    May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
  • Tissue specificity

    Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
  • Sequence similarities

    Belongs to the APP family.
    Contains 1 BPTI/Kunitz inhibitor domain.
  • Post-translational
    modifications

    The BPTI/Kunitz inhibitor domain is O-glycosylated.
  • Cellular localization

    Cell membrane. Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • amyloid beta (A4) precursor like protein 2 antibody
    • Amyloid like protein 2 antibody
    • Amyloid precursor protein homolog HSD 2 antibody
    • amyloid precursor protein homolog HSD2 antibody
    • Amyloid protein homolog antibody
    • Amyloid-like protein 2 antibody
    • APLP-2 antibody
    • Aplp2 antibody
    • APLP2_HUMAN antibody
    • APPH antibody
    • APPL2 antibody
    • CDEBP antibody
    • CDEI box binding protein antibody
    • CDEI box-binding protein antibody
    see all

Images

  • All lanes : Anti-APLP2 antibody - C-terminal (ab190925) at 0.5 µg/ml

    Lane 1 : Rat brain tissue lysate
    Lane 2 : Rat heart tissue lysate
    Lane 3 : SMMC cell lysate

    Predicted band size: 87 kDa

References

ab190925 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab190925.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up