Key features and details
- Rabbit polyclonal to APLP2 (phospho Y755)
- Suitable for: IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-APLP2 (phospho Y755) antibody
See all APLP2 primary antibodies
DescriptionRabbit polyclonal to APLP2 (phospho Y755)
Specificityab193672 detects endogenous levels of APLP2 only when phosphorylated at tyrosine 755.
Tested applicationsSuitable for: IHC-Pmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Synthetic peptide within Human APLP2 (phospho Y755) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary. Peptide sequence is around phosphorylation site of tyrosine 755 (P-T-Y(p)-K-Y) .
Database link: Q06481
- Human brain tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol, 0.87% Sodium chloride, 59% PBS
PBS is without Mg2+ and Ca2+.
Concentration information loading...
PurityImmunogen affinity purified
Purification notesNon-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
Our Abpromise guarantee covers the use of ab193672 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||1/50 - 1/100.|
FunctionMay play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
Tissue specificityExpressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
Sequence similaritiesBelongs to the APP family.
Contains 1 BPTI/Kunitz inhibitor domain.
modificationsThe BPTI/Kunitz inhibitor domain is O-glycosylated.
Cellular localizationCell membrane. Nucleus.
- Information by UniProt
- amyloid beta (A4) precursor like protein 2 antibody
- Amyloid like protein 2 antibody
- Amyloid precursor protein homolog HSD 2 antibody
ab193672 has not yet been referenced specifically in any publications.