Overview

  • Product name

    Anti-APLP2 (phospho Y755) antibody
    See all APLP2 primary antibodies
  • Description

    Rabbit polyclonal to APLP2 (phospho Y755)
  • Host species

    Rabbit
  • Specificity

    ab193672 detects endogenous levels of APLP2 only when phosphorylated at tyrosine 755.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide within Human APLP2 (phospho Y755) conjugated to Keyhole Limpet Haemocyanin (KLH). The exact sequence is proprietary. Peptide sequence is around phosphorylation site of tyrosine 755 (P-T-Y(p)-K-Y) .
    Database link: Q06481

  • Positive control

    • Human brain tissue.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.40
    Preservative: 0.02% Sodium azide
    Constituents: 40% Glycerol, 0.87% Sodium chloride, 59% PBS

    PBS is without Mg2+ and Ca2+.
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Purification notes

    Non-phospho specific antibodies were removed by chromatography using non-phosphopeptide.
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab193672 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/50 - 1/100.

Target

  • Function

    May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
  • Tissue specificity

    Expressed in placenta, brain, heart, lung, liver, kidney and endothelial tissues.
  • Sequence similarities

    Belongs to the APP family.
    Contains 1 BPTI/Kunitz inhibitor domain.
  • Post-translational
    modifications

    The BPTI/Kunitz inhibitor domain is O-glycosylated.
  • Cellular localization

    Cell membrane. Nucleus.
  • Information by UniProt
  • Database links

  • Alternative names

    • amyloid beta (A4) precursor like protein 2 antibody
    • Amyloid like protein 2 antibody
    • Amyloid precursor protein homolog HSD 2 antibody
    • amyloid precursor protein homolog HSD2 antibody
    • Amyloid protein homolog antibody
    • Amyloid-like protein 2 antibody
    • APLP-2 antibody
    • Aplp2 antibody
    • APLP2_HUMAN antibody
    • APPH antibody
    • APPL2 antibody
    • CDEBP antibody
    • CDEI box binding protein antibody
    • CDEI box-binding protein antibody
    see all

Images

  • Immunohistochemical analysis of formalin-fixed, paraffin-embedded Human brain tissue sections labeling APLP2 (phospho Y755) with ab193672 at a 1/50 dilution. The image on the right was preincubated with blocking peptide.

References

ab193672 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab193672.
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