Overview

  • Product name

  • Description

    Goat polyclonal to Apo-M
  • Host species

    Goat
  • Tested applications

    Suitable for: WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat
  • Immunogen

    Synthetic peptide corresponding to Mouse Apo-M (internal sequence) conjugated to keyhole limpet haemocyanin.
    Database link: NP_061286.1

  • Positive control

    • Human Liver tissue; Human placenta lysate.

Properties

Applications

Our Abpromise guarantee covers the use of ab122896 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use a concentration of 0.3 - 1 µg/ml. Detects a band of approximately 26 kDa (predicted molecular weight: 21 kDa).
IHC-P Use a concentration of 3.75 µg/ml.

Target

  • Function

    Probably involved in lipid transport. Can bind sphingosine-1-phosphate, myristic acid, palmitic acid and stearic acid, retinol, all-trans-retinoic acid and 9-cis-retinoic acid.
  • Tissue specificity

    Plasma protein. Expressed in liver and kidney.
  • Sequence similarities

    Belongs to the calycin superfamily. Lipocalin family. Highly divergent.
  • Cellular localization

    Secreted. Present in high density lipoprotein (HDL) and to a lesser extent in triglyceride-rich lipoproteins (TGRLP) and low density lipoproteins.
  • Information by UniProt
  • Database links

  • Alternative names

    • Apo M antibody
    • Apo-M antibody
    • Apolipoprotein M antibody
    • ApoM antibody
    • APOM_HUMAN antibody
    • G3A antibody
    • HSPC336 antibody
    • MGC22400 antibody
    • NG20 antibody
    • NG20 like protein antibody
    • Protein G3a antibody
    see all

Images

  • ab122896, at 3.75 µg/ml, staining Apo-M in Formalin-fixed, Paraffin-embedded Human Liver tissue by Immunohistochemistry.

  • Anti-Apo-M antibody (ab122896) at 0.5 µg/ml + Human placenta lysate (in RIPA buffer) at 35 µg

    Developed using the ECL technique.

    Predicted band size: 21 kDa



    The observed molecular weight corresponds to earlier findings in literature with different antibodies (Xu and Dahlbck, J Biol Chem. 1999 Oct 29;274(44):31286-90.; PMID: 10531326).

References

This product has been referenced in:

  • Liu J  et al. Atorvastatin upregulates apolipoprotein M expression via attenuating LXRa expression in hyperlipidemic apoE-deficient mice. Exp Ther Med 16:3785-3792 (2018). Read more (PubMed: 30344653) »
See 1 Publication for this product

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