Overview

  • Product name

    Anti-APOBEC3C/PBI antibody
    See all APOBEC3C/PBI primary antibodies
  • Description

    Rabbit polyclonal to APOBEC3C/PBI
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IFmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Gorilla
  • Immunogen

    Recombinant fragment corresponding to Human APOBEC3C/PBI aa 23-49.
    Sequence:

    NLWEANDRNETWLCFTVEGIKRRSVVS


    Database link: Q9NRW3

  • Positive control

    • ICC/IF: U-2 OS cells.
  • General notes

     This product was previously labelled as APOBEC3C

     

Properties

Applications

Our Abpromise guarantee covers the use of ab221874 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 1 - 4 µg/ml.

Fixation/Permeabilization: PFA/Triton X-100.

Target

  • Function

    Host cellular restriction factor that may have antiviral activities against exogenous and endogenous viruses, as well as retrotransposons. May also play a role in the epigenetic regulation of gene expression through the process of active DNA demethylation.
  • Tissue specificity

    Expressed in spleen, testes, peripherical blood lymphocytes, heart, thymus, prostate and ovary.
  • Sequence similarities

    Belongs to the cytidine and deoxycytidylate deaminase family.
  • Information by UniProt
  • Database links

  • Alternative names

    • A3C antibody
    • ABC3C_HUMAN antibody
    • APOBEC1 like antibody
    • APOBEC1-like antibody
    • APOBEC1L antibody
    • APOBEC3C antibody
    • Apolipoprotein B mRNA editing enzyme catalytic polypeptide like 3C antibody
    • ARDC2 antibody
    • ARDC4 antibody
    • ARP5 antibody
    • bK150C2.3 antibody
    • DNA dC >dU editing enzyme APOBEC 3C antibody
    • MGC19485 antibody
    • PBI antibody
    • Phorbolin I antibody
    • Phorbolin I protein antibody
    • Probable DNA dC dU editing enzyme APOBEC 3C antibody
    • Probable DNA dC->dU-editing enzyme APOBEC-3C antibody
    see all

Images

  • PFA-fixed, Triton X-100 permeabilized U-2 OS (human bone osteosarcoma epithelial cell line) cells stained for APOBEC3C/PBI (green) using ab221874 at 4 ug/ml in ICC/IF.

References

ab221874 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab221874.
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