Overview

  • Product name

    Anti-Apolipoprotein B antibody
    See all Apolipoprotein B primary antibodies
  • Description

    Rabbit polyclonal to Apolipoprotein B
  • Host species

    Rabbit
  • Tested applications

    Suitable for: WB, IHC-P, RIDmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Full length native protein (purified) corresponding to Mouse Apolipoprotein B. Mouse very low density lipoprotein.

  • Positive control

    • Human Liver tissue.

Applications

Our Abpromise guarantee covers the use of ab125128 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB Use at an assay dependent concentration. Predicted molecular weight: 516 kDa.
IHC-P 1/100.
RID Use at an assay dependent concentration.

Target

  • Function

    Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
  • Involvement in disease

    Hypobetalipoproteinemia, familial, 1
    Familial ligand-defective apolipoprotein B-100
    Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.
  • Sequence similarities

    Contains 1 vitellogenin domain.
  • Post-translational
    modifications

    Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
  • Cellular localization

    Cytoplasm. Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • Apo B-100 antibody
    • Apo B-48 antibody
    • ApoB 100 antibody
    • ApoB 48 antibody
    • APOB antibody
    • APOB_HUMAN antibody
    • Apolipoprotein B (including Ag(x) antigen) antibody
    • Apolipoprotein B 100 antibody
    • Apolipoprotein B antibody
    • Apolipoprotein B-48 antibody
    • Apolipoprotein B48 antibody
    • FLDB antibody
    • LDLCQ4 antibody
    see all

Images

  • ab125128 at 1/100 dilution staining Apolipoprotein B in formalin-fixed, paraffin-embedded Human liver tissue by Immunohistochemistry.

References

ab125128 has not yet been referenced specifically in any publications.

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