Anti-Apolipoprotein B antibody (ab13993)
- Datasheet
- References (1)
- Protocols
Overview
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Product nameAnti-Apolipoprotein B antibody
See all Apolipoprotein B primary antibodies -
DescriptionChicken polyclonal to Apolipoprotein B
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Host speciesChicken
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Tested applicationsSuitable for: ELISA, WBmore details
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Species reactivityReacts with: Human
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Immunogen
Full length protein (Human).
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
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Storage bufferConstituent: PBS
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Concentration information loading... -
PurityImmunogen affinity purified
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Purification notesPeptide immunogen affinity column.
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ClonalityPolyclonal
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IsotypeIgY
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Research areas
Associated products
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Isotype control
Applications
Our Abpromise guarantee covers the use of ab13993 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ELISA | Use at an assay dependent dilution. | |
| WB | Use at an assay dependent dilution. Predicted molecular weight: 506 kDa. |
Target
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FunctionApolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
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Involvement in diseaseHypobetalipoproteinemia, familial, 1
Familial ligand-defective apolipoprotein B-100
Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia. -
Sequence similaritiesContains 1 vitellogenin domain.
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Post-translational
modificationsPalmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle. -
Cellular localizationCytoplasm. Secreted.
- Information by UniProt
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Database links
- Entrez Gene: 338 Human
- Omim: 107730 Human
- SwissProt: P04114 Human
- Unigene: 120759 Human
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Alternative names
- Apo B-100 antibody
- Apo B-48 antibody
- ApoB 100 antibody
see all
Datasheets and documents
Protocols
References
This product has been referenced in:
- Von Wald T et al. Age-related variations in follicular apolipoproteins may influence human oocyte maturation and fertility potential. Fertil Steril 93:2354-61 (2010). Read more (PubMed: 19230882) »
