Overview

  • Product name

    Anti-Apolipoprotein B antibody
    See all Apolipoprotein B primary antibodies
  • Description

    Goat polyclonal to Apolipoprotein B
  • Host species

    Goat
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Apolipoprotein B aa 3984-3995 (internal sequence) (Cysteine residue). (NP_000375.2).
    Sequence:

    C-TDLHLRYQKDKK


    Database link: P04114

  • Positive control

    • IHC-P: Human liver and small intestine tissues.

Properties

Applications

Our Abpromise guarantee covers the use of ab223625 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P Use a concentration of 2 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Function

    Apolipoprotein B is a major protein constituent of chylomicrons (apo B-48), LDL (apo B-100) and VLDL (apo B-100). Apo B-100 functions as a recognition signal for the cellular binding and internalization of LDL particles by the apoB/E receptor.
  • Involvement in disease

    Hypobetalipoproteinemia, familial, 1
    Familial ligand-defective apolipoprotein B-100
    Defects in APOB associated with defects in other genes (polygenic) can contribute to hypocholesterolemia.
  • Sequence similarities

    Contains 1 vitellogenin domain.
  • Post-translational
    modifications

    Palmitoylated; structural requirement for proper assembly of the hydrophobic core of the lipoprotein particle.
  • Cellular localization

    Cytoplasm. Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • Apo B 100 antibody
    • Apo B antibody
    • Apo B-100 antibody
    • Apo B-48 antibody
    • Apo B100 antibody
    • Apo B48 antibody
    • ApoB 100 antibody
    • ApoB 48 antibody
    • APOB antibody
    • APOB_HUMAN antibody
    • Apolipoprotein B (including Ag(x) antigen) antibody
    • Apolipoprotein B 100 antibody
    • Apolipoprotein B 48 antibody
    • Apolipoprotein B antibody
    • Apolipoprotein B-48 antibody
    • Apolipoprotein B100 antibody
    • Apolipoprotein B48 antibody
    • FLDB antibody
    • LDLCQ4 antibody
    see all

Images

  • Paraffin-embedded human small intestine tissue stained for Apolipoprotein B with ab223625 at 2 µg/ml in immunohistochemical analysis, followed by AP-staining.

  • Paraffin-embedded human liver tissue stained for Apolipoprotein B with ab223625 at 2 µg/ml in immunohistochemical analysis, followed by AP-staining.

References

ab223625 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab223625.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up