Overview

  • Product name

    Anti-Apolipoprotein CII/ApoC-II antibody
    See all Apolipoprotein CII/ApoC-II primary antibodies
  • Description

    Rabbit polyclonal to Apolipoprotein CII/ApoC-II
  • Host species

    Rabbit
  • Specificity

    Ab20952 specifically binds to human Apo CII.
  • Tested applications

    Suitable for: WB, ELISAmore details
  • Species reactivity


    Predicted to work with: Human
  • Immunogen

    Full length protein corresponding to Human Apolipoprotein CII/ApoC-II.

  • General notes

     This product was previously labelled as Apolipoprotein CII

     

Properties

Applications

Our Abpromise guarantee covers the use of ab20952 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/10000 - 1/80000. Predicted molecular weight: 11 kDa. Dilution optimised using Chromogenic detection. Can be used to detect the existence of Apo CII in plasma and lipoproteins.
ELISA 1/10000 - 1/80000.

Target

  • Function

    Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL.
  • Tissue specificity

    Liver and intestine.
  • Involvement in disease

    Hyperlipoproteinemia 1B
  • Sequence similarities

    Belongs to the apolipoprotein C2 family.
  • Post-translational
    modifications

    Proapolipoprotein C-II is synthesized as a sialic acid containing glycoprotein which is subsequently desialylated prior to its proteolytic processing.
    Proapolipoprotein C-II, the major form found in plasma undergoes proteolytic cleavage of its N-terminal hexapeptide to generate apolipoprotein C-II, which occurs as the minor form in plasma.
  • Cellular localization

    Secreted.
  • Information by UniProt
  • Database links

  • Alternative names

    • APC 2 antibody
    • APC2 antibody
    • Apo CII antibody
    • Apo-CII antibody
    • APOC 2 antibody
    • ApoC II antibody
    • ApoC-II antibody
    • APOC2 antibody
    • APOC2 protein antibody
    • APOC2_HUMAN antibody
    • ApoCII antibody
    • Apolipoprotein C II antibody
    • Apolipoprotein C II precursor antibody
    • Apolipoprotein C2 antibody
    • ApolipoproteinCII antibody
    • MGC75082 antibody
    • ProapoC-II antibody
    • Proapolipoprotein C-II antibody
    see all

References

ab20952 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab20952.
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