Overview

  • Product name
    Anti-Apolipoprotein CII/ApoC-II antibody (HRP)
    See all Apolipoprotein CII/ApoC-II primary antibodies
  • Description
    Goat polyclonal to Apolipoprotein CII/ApoC-II (HRP)
  • Host species
    Goat
  • Conjugation
    HRP
  • Tested applications
    Suitable for: WB, ELISAmore details
  • Species reactivity
    Reacts with: Human
  • Immunogen

    Synthetic peptide corresponding to Human Apolipoprotein CII/ApoC-II.

  • General notes

     This product was previously labelled as Apolipoprotein CII

     

Properties

Applications

Our Abpromise guarantee covers the use of ab27623 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/500 - 1/2000. Predicted molecular weight: 11 kDa.



The antibody can be used to detect human Apolipoprotein CII/ApoC-II in plasma, immunoassays and immunoblots.

ELISA 1/500 - 1/2000.

Target

  • Function
    Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL.
  • Tissue specificity
    Liver and intestine.
  • Involvement in disease
    Hyperlipoproteinemia 1B
  • Sequence similarities
    Belongs to the apolipoprotein C2 family.
  • Post-translational
    modifications
    Proapolipoprotein C-II is synthesized as a sialic acid containing glycoprotein which is subsequently desialylated prior to its proteolytic processing.
    Proapolipoprotein C-II, the major form found in plasma undergoes proteolytic cleavage of its N-terminal hexapeptide to generate apolipoprotein C-II, which occurs as the minor form in plasma.
  • Cellular localization
    Secreted.
  • Information by UniProt
  • Database links
  • Alternative names
    • APC 2 antibody
    • APC2 antibody
    • Apo CII antibody
    • Apo-CII antibody
    • APOC 2 antibody
    • ApoC II antibody
    • ApoC-II antibody
    • APOC2 antibody
    • APOC2 protein antibody
    • APOC2_HUMAN antibody
    • ApoCII antibody
    • Apolipoprotein C II antibody
    • Apolipoprotein C II precursor antibody
    • Apolipoprotein C2 antibody
    • ApolipoproteinCII antibody
    • MGC75082 antibody
    • ProapoC-II antibody
    • Proapolipoprotein C-II antibody
    see all

References

ab27623 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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