Recombinant Anti-APRIL/TNFSF13 antibody [EPR4286] (ab108206)
Key features and details
- Produced recombinantly (animal-free) for high batch-to-batch consistency and long term security of supply
- Rabbit monoclonal [EPR4286] to APRIL/TNFSF13
- Suitable for: WB
- Reacts with: Mouse, Rat, Human
Related conjugates and formulations
Overview
-
Product name
Anti-APRIL/TNFSF13 antibody [EPR4286]
See all APRIL/TNFSF13 primary antibodies -
Description
Rabbit monoclonal [EPR4286] to APRIL/TNFSF13 -
Host species
Rabbit -
Tested applications
Suitable for: WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
-
Positive control
- Raji, Jurkat, HeLa, PC-12 or NIH 3T3 cell lysate.
-
General notes
This product is a recombinant monoclonal antibody, which offers several advantages including:
- - High batch-to-batch consistency and reproducibility
- - Improved sensitivity and specificity
- - Long-term security of supply
- - Animal-free production
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb® patents.
Properties
-
Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
Storage buffer
pH: 7.20
Preservative: 0.05% Sodium azide
Constituents: 0.1% BSA, 40% Glycerol (glycerin, glycerine), 9.85% Tris glycine, 50% Tissue culture supernatant -
Concentration information loading...
-
Purity
Tissue culture supernatant -
Clonality
Monoclonal -
Clone number
EPR4286 -
Isotype
IgG -
Research areas
Associated products
-
Alternative Versions
-
Isotype control
-
Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab108206 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Application | Abreviews | Notes |
---|---|---|
WB |
1/1000 - 1/10000. Predicted molecular weight: 27 kDa.
|
Notes |
---|
WB
1/1000 - 1/10000. Predicted molecular weight: 27 kDa. |
Target
-
Function
Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. May be implicated in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes. -
Tissue specificity
Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages. -
Sequence similarities
Belongs to the tumor necrosis factor family. -
Post-translational
modificationsThe precursor is cleaved by furin. -
Cellular localization
Secreted. - Information by UniProt
-
Database links
- Entrez Gene: 8741 Human
- Entrez Gene: 69583 Mouse
- Entrez Gene: 287437 Rat
- Omim: 604472 Human
- SwissProt: O75888 Human
- SwissProt: Q9D777 Mouse
- Unigene: 54673 Human
- Unigene: 8983 Mouse
-
Alternative names
- A proliferation inducing ligand antibody
- A proliferation-inducing ligand antibody
- APRIL antibody
see all
Images
Protocols
Datasheets and documents
-
SDS download
-
Datasheet download
References (0)
ab108206 has not yet been referenced specifically in any publications.