Anti-Aquaporin 1 antibody (ab15080)
Key features and details
- Rabbit polyclonal to Aquaporin 1
- Suitable for: ELISA
- Isotype: IgG
Overview
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Product name
Anti-Aquaporin 1 antibody
See all Aquaporin 1 primary antibodies -
Description
Rabbit polyclonal to Aquaporin 1 -
Host species
Rabbit -
Tested applications
Suitable for: ELISAmore details -
Immunogen
A 19 amino acid synthetic peptide within the carboxy terminal domain of rat Aquaporin 1 that is 100% homologous in mouse, rat, human and Bovine. This domain is predicted to be cytoplasmic.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Add glycerol to a final volume of 50% for extra stability and aliquot. Store at -20°C. Avoid freeze / thaw cycle. -
Storage buffer
Preservative: 0.05% Sodium azide
Constituent: PBS -
Concentration information loading... -
Purity
Whole antiserum -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Recombinant Protein
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab15080 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| ELISA |
Use at an assay dependent concentration.
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| Notes |
|---|
|
ELISA
Use at an assay dependent concentration. |
Target
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Function
Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. -
Tissue specificity
Expressed in a number of tissues including erythrocytes, renal tubules, retinal pigment epithelium, heart, lung, skeletal muscle, kidney and pancreas. Weakly expressed in brain, placenta and liver. -
Sequence similarities
Belongs to the MIP/aquaporin (TC 1.A.8) family. -
Domain
Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA). -
Cellular localization
Membrane. - Information by UniProt
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Alternative names
- AQP 1 antibody
- AQP CHIP antibody
- AQP-1 antibody
see all
Images
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ELISA - Anti-Aquaporin 1 antibody (ab15080)
Antibody titer determination against Aquaporin-1 using pre-immunised serum, Antiserum and Affinity purified Anti-Aquaporin 1 (Cat: ab15080).
Protocols
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
References (42)
ab15080 has been referenced in 42 publications.
- Wang J et al. Bax inhibitor 1 preserves mitochondrial homeostasis in acute kidney injury through promoting mitochondrial retention of PHB2. Theranostics 10:384-397 (2020). PubMed: 31903127
- McCrimmon A et al. Comprehensive assessment of mitochondrial respiratory function in freshly isolated nephron segments. Am J Physiol Renal Physiol 318:F1237-F1245 (2020). PubMed: 32223308
- Lv Y et al. 1a,25-dihydroxyvitamin D3 attenuates oxidative stress-induced damage in human trabecular meshwork cells by inhibiting TGFß-SMAD3-VDR pathway. Biochem Biophys Res Commun 516:75-81 (2019). PubMed: 31196627
- Dalghi MG et al. Expression and distribution of PIEZO1 in the mouse urinary tract. Am J Physiol Renal Physiol 317:F303-F321 (2019). PubMed: 31166705
- Chamanza R et al. Normal Anatomy, Histology, and Spontaneous Pathology of the Kidney, and Selected Renal Biomarker Reference Ranges in the Cynomolgus Monkey. Toxicol Pathol 47:612-633 (2019). PubMed: 31409264
