Aquaporin 3 peptide (ab195690)

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Key features and details

  • Suitable for: Blocking

Description

  • Product name

    Aquaporin 3 peptide

  • Animal free

    No

  • Nature

    Synthetic

    • Sequence

      EENVKLAHVKHKEQI

    • Amino acids

      278 to 292

Associated products

Specifications

Our Abpromise guarantee covers the use of ab195690 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • Applications

    Blocking - Blocking peptide for Anti-Aquaporin 3 antibody (ab125219)

  • Form

    Liquid
  • Concentration information loading...

Preparation and Storage

  • Stability and Storage

    Shipped at 4°C. Store at -20°C.

General Info

  • Alternative names

    • AQP 3
    • AQP-3
    • Aqp3
    • AQP3_HUMAN
    • Aquaglyceroporin-3
    • Aquaporin 3 (GIL blood group)
    • Aquaporin 3 (Gill blood group)
    • Aquaporin-3
    • Aquaporin3
    • GIL
    • Gill blood group
    see all

  • Function

    Water channel required to promote glycerol permeability and water transport across cell membranes. Acts as a glycerol transporter in skin and plays an important role in regulating SC (stratum corneum) and epidermal glycerol content. Involved in skin hydration, wound healing, and tumorigenesis. Provides kidney medullary collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Slightly permeable to urea and may function as a water and urea exit mechanism in antidiuresis in collecting duct cells. It may play an important role in gastrointestinal tract water transport and in glycerol metabolism.

  • Tissue specificity

    Widely expressed in epithelial cells of kidney (collecting ducts) and airways, in keratinocytes, immature dendritic cells and erythrocytes. Isoform 2 is not detectable in erythrocytes at the protein level.

  • Sequence similarities

    Belongs to the MIP/aquaporin (TC 1.A.8) family.

  • Domain

    Aquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).

  • Cellular localization

    Basolateral cell membrane. In collecting ducts of kidney.
  • Information by UniProt

Protocols

To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.

Click here to view the general protocols

References (1)

Publishing research using ab195690? Please let us know so that we can cite the reference in this datasheet.

ab195690 has been referenced in 1 publication.

  • Prieto-Martínez N  et al. Relationship of aquaporins 3 (AQP3), 7 (AQP7), and 11 (AQP11) with boar sperm resilience to withstand freeze-thawing procedures. Andrology 5:1153-1164 (2017). PubMed: 28941027

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