Key features and details
- Rabbit polyclonal to Aquaporin 4
- Suitable for: WB
- Reacts with: Rat, Human
- Isotype: IgG
Product nameAnti-Aquaporin 4 antibody
See all Aquaporin 4 primary antibodies
DescriptionRabbit polyclonal to Aquaporin 4
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Rat, Human
Predicted to work with: Mouse
A synthetic peptide corresponding to a sequence at the C-terminal of Human Aquaporin 4
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Storage bufferPreservatives: 0.025% Sodium azide, 0.025% Thimerosal (merthiolate)
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab81355 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa.|
FunctionForms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.
Tissue specificityBrain - muscle >> heart, kidney, lung, and trachea.
Sequence similaritiesBelongs to the MIP/aquaporin (TC 1.A.8) family.
DomainAquaporins contain two tandem repeats each containing three membrane-spanning domains and a pore-forming loop with the signature motif Asn-Pro-Ala (NPA).
modificationsPhosphorylation by PKC at Ser-180 reduces conductance by 50%. Phosphorylation by PKG at Ser-111 in response to glutamats increases conductance by 40%.
- Information by UniProt
- AQP 4 antibody
- AQP-4 antibody
- AQP4 antibody
All lanes : Anti-Aquaporin 4 antibody (ab81355) at 1 µg/ml
Lane 1 : Tissue lysates prepared from Rat heart tissue.
Lane 2 : Tissue lysates prepared from Rat kidney tissue.
Lanes 3-4 : Tissue lysates prepared from Rat brain tissue.
Lysates/proteins at 50 µg per lane.
All lanes : HRP-conjugated Goat anti-rabbit IgG at 1/3000 dilution
Predicted band size: 35 kDa
ab81355 has been referenced in 1 publication.
- Tang H et al. Down-regulated expression of aquaporin-4 in the cerebellum after status epilepticus. Cogn Neurodyn 11:183-188 (2017). PubMed: 28348649