DNA synthesis inhibitor. DNA ligase and polymerase inhibitor. Anticancer agent.
Store at -20°C (desiccating conditions).
Supplied in water (10 mM)
Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Negoro E et al. Characterization of cytarabine-resistant leukemic cell lines established from five different blood cell lineages using gene expression and proteomic analyses. Int J Oncol38:911-9 (2011).
Read more (PubMed: 21290089) »
Yamauchi T et al. Intracellular cytarabine triphosphate production correlates to deoxycytidine kinase/cytosolic 5'-nucleotidase II expression ratio in primary acute myeloid leukemia cells. Biochem Pharmacol77:1780-6 (2009).
Read more (PubMed: 19428333) »
Nishi R et al. A new, simple method for quantifying gemcitabine triphosphate in cancer cells using isocratic high-performance liquid chromatography. Cancer Sci97:1274-8 (2006).
Read more (PubMed: 17034368) »
Colón-Cesario M et al. An inhibitor of DNA recombination blocks memory consolidation, but not reconsolidation, in context fear conditioning. J Neurosci26:5524-33 (2006).
Read more (PubMed: 16707804) »