Ara-cytidine-5'-triphosphate (ara-CTP) (aqueous solution), DNA synthesis inhibitor (ab146751)

Overview

  • Product name

    Ara-cytidine-5'-triphosphate (ara-CTP) (aqueous solution), DNA synthesis inhibitor
  • Description

    DNA synthesis inhibitor
  • Alternative names

    • ara-CTP
    • Cytarabine triphosphate
    • Cytidine-arabinofuranoside-5’-triphosphate
  • Biological description

    DNA synthesis inhibitor. DNA ligase and polymerase inhibitor. Anticancer agent.

  • Purity

    > 95%
  • CAS Number

    13191-15-6
  • Chemical structure

    Chemical Structure

Properties

  • Molecular weight

    483.15
  • Molecular formula

    C9H16N3O14P3
  • Storage instructions

    Store at -20°C (desiccating conditions).
  • Solubility overview

    Supplied in water (10 mM)
  • Handling

    Providing storage is as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 6 months. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • Source

    Synthetic

References

This product has been referenced in:

  • Negoro E  et al. Characterization of cytarabine-resistant leukemic cell lines established from five different blood cell lineages using gene expression and proteomic analyses. Int J Oncol 38:911-9 (2011). Read more (PubMed: 21290089) »
  • Yamauchi T  et al. Intracellular cytarabine triphosphate production correlates to deoxycytidine kinase/cytosolic 5'-nucleotidase II expression ratio in primary acute myeloid leukemia cells. Biochem Pharmacol 77:1780-6 (2009). Read more (PubMed: 19428333) »
  • Nishi R  et al. A new, simple method for quantifying gemcitabine triphosphate in cancer cells using isocratic high-performance liquid chromatography. Cancer Sci 97:1274-8 (2006). Read more (PubMed: 17034368) »
  • Colón-Cesario M  et al. An inhibitor of DNA recombination blocks memory consolidation, but not reconsolidation, in context fear conditioning. J Neurosci 26:5524-33 (2006). Read more (PubMed: 16707804) »

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Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES, NOT FOR USE IN HUMANS"
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