Overview

  • Product name

    Anti-Arg2 antibody [AT7F8]
    See all Arg2 primary antibodies
  • Description

    Mouse monoclonal [AT7F8] to Arg2
  • Host species

    Mouse
  • Tested applications

    Suitable for: WBmore details
  • Species reactivity

    Reacts with: Human
    Predicted to work with: Mouse, Rat, Rabbit, Cow
  • Immunogen

    Recombinant full length protein corresponding to Human Arg2 aa 23-354. Purified from E.coli. NCBI Accession No.: NP_001163.
    Database link: P78540

  • Positive control

    • WB - SW480 cell lysate
  • General notes

    This product was changed from ascites to tissue culture supernatant on 07/06/2019. Please note that the dilutions may need to be adjusted accordingly. If you have any questions, please do not hesitate to contact our scientific support team.

Properties

Applications

Our Abpromise guarantee covers the use of ab219257 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
WB 1/1000. Predicted molecular weight: 39 kDa.

Target

  • Function

    May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
  • Tissue specificity

    Expressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas.
  • Pathway

    Nitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.
  • Sequence similarities

    Belongs to the arginase family.
  • Cellular localization

    Mitochondrion.
  • Information by UniProt
  • Database links

  • Alternative names

    • ARG2 antibody
    • ARGI2_HUMAN antibody
    • Arginase II mitochondrial antibody
    • Arginase type II antibody
    • Arginase-2 antibody
    • arginase-2, mitochondrial antibody
    • Kidney arginase antibody
    • Kidney type arginase antibody
    • Kidney-type arginase antibody
    • L arginine amidinohydrolase antibody
    • L arginine ureahydrolase antibody
    • mitochondrial antibody
    • Non hepatic arginase antibody
    • Non-hepatic arginase antibody
    • Nonhepatic arginase antibody
    • Type II arginase antibody
    see all

Images

  • Anti-Arg2 antibody [AT7F8] (ab219257) at 1/1000 dilution + SW480 cells at 40 µg

    Secondary
    goat anti-mouse antibody

    Developed using the ECL technique.

    Predicted band size: 39 kDa

References

ab219257 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

There are currently no Customer reviews or Questions for ab219257.
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