Key features and details
- Rabbit polyclonal to Arg2 - N-terminal
- Suitable for: IHC-P, WB
- Reacts with: Rat, Human
- Isotype: IgG
Product nameAnti-Arg2 antibody - N-terminal
See all Arg2 primary antibodies
DescriptionRabbit polyclonal to Arg2 - N-terminal
SpecificityNo cross reactivity with other proteins.
Tested applicationsSuitable for: IHC-P, WBmore details
Species reactivityReacts with: Rat, Human
Predicted to work with: Mouse, Rabbit, Cow
- Rat lung, rat testis, A549 and 293T cell lysates; Human mammary cancer tissue.
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Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferPreservatives: 0.025% Thimerosal (merthiolate), 0.025% Sodium azide
Constituents: 2.5% BSA, 0.45% Sodium chloride, 0.1% Dibasic monohydrogen sodium phosphate
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab191029 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|IHC-P||Use a concentration of 0.5 - 1 µg/ml. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
|WB||Use a concentration of 0.1 - 0.5 µg/ml. Predicted molecular weight: 39 kDa.|
FunctionMay play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to NO synthase. Since NO synthase is found in the penile corpus cavernosum smooth muscle, the clitoral corpus cavernosum and the vagina, arginase II plays a role in both male and female sexual arousal. It is therefore a potential target for the treatment of male and female sexual arousal disorders.
Tissue specificityExpressed most strongly in kidney and prostate, much less strongly in the brain, skeletal muscle, placenta, lung, mammary gland, macrophage, uterus, testis and gut, but apparently not in the liver, heart and pancreas.
PathwayNitrogen metabolism; urea cycle; L-ornithine and urea from L-arginine: step 1/1.
Sequence similaritiesBelongs to the arginase family.
- Information by UniProt
- ARG2 antibody
- ARGI2_HUMAN antibody
- Arginase II mitochondrial antibody
Immunohistochemical analysis of Paraffin-embedded Human mammary cancer tissue labeling Arg2 with ab191029 at 1 µg/ml.
All lanes : Anti-Arg2 antibody - N-terminal (ab191029) at 0.5 µg/ml
Lane 1 : Rat lung tissue lysate
Lane 2 : Rat testis tissue lysate
Lane 3 : A549 cell lysate
Lane 4 : 293T cell lysate
Predicted band size: 39 kDa
ab191029 has not yet been referenced specifically in any publications.