Key features and details
- Rabbit polyclonal to ARHGAP22
- Suitable for: WB, IHC-P
- Reacts with: Human
- Isotype: IgG
Product nameAnti-ARHGAP22 antibody
DescriptionRabbit polyclonal to ARHGAP22
Tested applicationsSuitable for: WB, IHC-Pmore details
Species reactivityReacts with: Human
- RT-4 cell lysate; Human testis tissue.
Storage instructionsShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
Storage bufferpH: 7.20
Preservative: 0.02% Sodium azide
Constituents: 40% Glycerol (glycerin, glycerine), 59% PBS
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab204743 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||Use a concentration of 0.04 - 0.4 µg/ml. Predicted molecular weight: 77 kDa.|
|IHC-P||1/50 - 1/200. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.|
FunctionRho GTPase-activating protein involved in the signal transduction pathway that regulates endothelial cell capillary tube formation during angiogenesis. Acts as a GTPase activator for the RAC1 by converting it to an inactive GDP-bound state. Inhibits RAC1-dependent lamellipodia formation. May also play a role in transcription regulation via its interaction with VEZF1, by regulating activity of the endothelin-1 (EDN1) promoter.
Sequence similaritiesContains 1 PH domain.
Contains 1 Rho-GAP domain.
Cellular localizationCytoplasm. Nucleus. Mainly cytoplasmic. Some fraction is nuclear.
- Information by UniProt
- ARHGAP22 antibody
- RHG22_HUMAN antibody
- Rho GTPase activating protein 2 antibody
ab204743 has not yet been referenced specifically in any publications.