Overview

  • Product name

    Anti-ARHGAP4 antibody - C-terminal
    See all ARHGAP4 primary antibodies
  • Description

    Rabbit polyclonal to ARHGAP4 - C-terminal
  • Host species

    Rabbit
  • Specificity

    ab198696 detects endogenous level of total ARHGAP4 protein.
  • Tested applications

    Suitable for: IHC-Pmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide within Human ARHGAP4 (C terminal). The exact sequence is proprietary. NCBI Accession No. NP_001657.
    Database link: P98171

  • Positive control

    • Human liver cancer and brain tissues.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.
  • Storage buffer

    pH: 7.3
    Preservative: 0.05% Sodium azide
    Constituents: 50% Glycerol, 49% PBS
  • Concentration information loading...
  • Purity

    Immunogen affinity purified
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab198696 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-P 1/25 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

Target

  • Relevance

    ARHGAP4 (Rho GTPase-activating protein 4) has an inhibitory effect on stress fiber organization. It is a member of the group of signaling proteins involved in regulation of the small GTP-binding proteins of the RAS superfamily.
  • Cellular localization

    Cytoplasmic
  • Database links

  • Alternative names

    • ARHGAP 4 antibody
    • C1 antibody
    • GTPase-activating protein, Rho, 4 antibody
    • KIAA0131 antibody
    • OTTHUMP00000026004 antibody
    • p115 antibody
    • RGC 1 antibody
    • RGC1 antibody
    • Rho GAP hematopoietic protein C1 antibody
    • Rho GAP hematopoietic protein C1 antibody
    • Rho GTPase activating protein 4 antibody
    • Rho type GTPase activating protein 4 antibody
    • RhoGAP 4 antibody
    • RhoGAP4 antibody
    • SrGAP4 antibody
    see all

Images

  • Immunohistochemical analysis of paraffin-embedded Human liver cancer tissue labeling ARHGAP4 using ab198696 at a 1/25 dilution.

  • Immunohistochemical analysis of paraffin-embedded Human brain tissue labeling ARHGAP4 using ab198696 at a 1/25 dilution.

References

This product has been referenced in:

  • Shen Y  et al. ARHGAP4 regulates the cell migration and invasion of pancreatic cancer by the HDAC2/ß-catenin signaling pathway. Carcinogenesis N/A:N/A (2019). Read more (PubMed: 30958531) »
  • Shen Y  et al. ARHGAP4 mediates the Warburg effect in pancreatic cancer through the mTOR and HIF-1a signaling pathways. Onco Targets Ther 12:5003-5012 (2019). Read more (PubMed: 31303760) »
See all 2 Publications for this product

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