Product nameAnti-ARHGEF14 antibody
See all ARHGEF14 primary antibodies
DescriptionRabbit polyclonal to ARHGEF14
Tested applicationsSuitable for: WBmore details
Species reactivityReacts with: Human
Predicted to work with: Mouse, Rat
Recombinant fragment, corresponding to a region within amino acids 54-307 of Human ARHGEF14 (NP_001106203).
- Molt-4 and Raji whole cell lysates; 293T, A431, H1299, HeLa and HepG2 whole cell lysate (ab7900)
Storage instructionsShipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol
Concentration information loading...
PurityImmunogen affinity purified
Our Abpromise guarantee covers the use of ab96395 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
|WB||1/500 - 1/3000. Predicted molecular weight: 128 kDa.|
FunctionGuanine nucleotide exchange factor that potentially links pathways that signal through RAC1, RHOA and CDC42. Catalyzes guanine nucleotide exchange on RHOA and CDC42 and interacts specifically with the GTP-bound form of RAC1, suggesting that it functions as an effector of RAC1. May also participate in axonal transport in the brain. Becomes activated and highly tumorigenic by truncation of the N-terminus (By similarity). Isoform 5 activates CDC42.
Sequence similaritiesBelongs to the MCF2 family.
Contains 1 CRAL-TRIO domain.
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.
Contains 1 SH3 domain.
Contains 1 spectrin repeat.
DomainThe CRAL-TRIO domain is involved in interaction with inositol phospholipids.
The DH domain is involved in interaction with CCPG1.
Cellular localizationCytoplasm. Cell membrane.
- Information by UniProt
- ARHGEF 14 antibody
- DBL''s big sister antibody
- DBS antibody
ab96395 has not yet been referenced specifically in any publications.