Recombinant Anti-ARHGEF6 antibody [EPR11700(2)] - BSA and Azide free (ab250770)
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- References
- Protocols
Overview
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Product name
Anti-ARHGEF6 antibody [EPR11700(2)] - BSA and Azide free
See all ARHGEF6 primary antibodies -
Description
Rabbit monoclonal [EPR11700(2)] to ARHGEF6 - BSA and Azide free -
Host species
Rabbit -
Tested applications
Suitable for: IHC-P, WBmore details -
Species reactivity
Reacts with: Mouse, Rat, Human -
Immunogen
Synthetic peptide within Human ARHGEF6 aa 700 to the C-terminus. The exact sequence is proprietary.
Database link: Q15052 -
General notes
Ab250770 is the carrier-free version of ab184569. This format is designed for use in antibody labeling, including fluorochromes, metal isotopes, oligonucleotides, enzymes.
Our carrier-free formats are supplied in a buffer free of BSA, sodium azide and glycerol for higher conjugation efficiency.
Use our conjugation kits for antibody conjugates that are ready-to-use in as little as 20 minutes with <1 minute hands-on-time and 100% antibody recovery: available for fluorescent dyes, HRP, biotin and gold.
ab250770 is compatible with the Maxpar® Antibody Labeling Kit from Fluidigm.
Maxpar® is a trademark of Fluidigm Canada Inc.
Our RabMAb® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMab® patents.
This product is a recombinant rabbit monoclonal antibody.
Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle. -
Storage buffer
Constituent: PBS -
Concentration information loading... -
Purity
Protein A purified -
Clonality
Monoclonal -
Clone number
EPR11700(2) -
Isotype
IgG -
Research areas
Associated products
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Alternative Versions
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Conjugation kits
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Positive Controls
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Recombinant Protein
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Related Products
Applications
Our Abpromise guarantee covers the use of ab250770 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| IHC-P | Use at an assay dependent concentration. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol. | |
| WB | Use at an assay dependent concentration. Detects a band of approximately 87 kDa (predicted molecular weight: 87 kDa). |
Target
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Function
Acts as a RAC1 guanine nucleotide exchange factor (GEF). -
Tissue specificity
Ubiquitous. -
Involvement in disease
Defects in ARHGEF6 are the cause of mental retardation X-linked type 46 (MRX46) [MIM:300436]. Mental retardation is a mental disorder characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. Non-syndromic mental retardation patients do not manifest other clinical signs. -
Sequence similarities
Contains 1 CH (calponin-homology) domain.
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.
Contains 1 SH3 domain. - Information by UniProt
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Database links
- Entrez Gene: 9459 Human
- Entrez Gene: 73341 Mouse
- Entrez Gene: 363509 Rat
- Omim: 300267 Human
- SwissProt: Q15052 Human
- SwissProt: Q8K4I3 Mouse
- SwissProt: Q5XXR3 Rat
- Unigene: 522795 Human
see all -
Alternative names
- Alpha Pix antibody
- Alpha-Pix antibody
- ARHG6_HUMAN antibody
see all
Datasheets and documents
References
ab250770 has not yet been referenced specifically in any publications.
