For the best experience on the Abcam website please upgrade to a modern browser such as
Rabbit polyclonal to ARIH2
Predicted to work with:
Chimpanzee, Rhesus monkey, Gorilla, Orangutan
Synthetic peptide corresponding to a region between residue 100 and 150 of Human ARIH2 (NP_006312.1).
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.09% Sodium Azide
Constituents: Tris citrate/phosphate buffer, pH 7-8
Concentration information loading...
Immunogen affinity purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Use at 2-5 µg/mg of lysate.
Is unsuitable for WB.
E3 ubiquitin-protein ligase mediating 'Lys-48'-and 'Lys-63'-linked polyubiquitination and subsequent proteasomal degradation of modified proteins. May play a role in myelopoiesis.
Widely expressed with higher expression in granulocytes.
Protein modification; protein ubiquitination.
Belongs to the RBR family. Ariadne subfamily.
Contains 1 IBR-type zinc finger. Contains 2 RING-type zinc fingers.
RING-type 1 and RING-type 2 are required for the inhibitory function in myelopoiesis.
Ubiquitinated. Ubiquitination promotes proteasomal degradation.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
all trans retinoic acid inducible RING finger antibody
Ari 2 antibody
Immunoprecipitation - Anti-ARIH2 antibody (ab101982)
Detection of ARIH2 by Western Blot of Immunprecipitate.
An antibody to ARIH2, at 0.4 µg/ml, staining ARIH2 in HeLa whole cell lysate immunoprecipitated using ab101982 at 3 µg/mg lysate (1 mg/IP; 20% of IP loaded/lane).
Detection: Chemiluminescence with an exposure time of 30 seconds.
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"