Aristolochic acid C, Aristolochic acid derivative (ab142620)

Overview

  • Product name

    Aristolochic acid C, Aristolochic acid derivative
  • Description

    Mycotoxin. Aristolochic acid derivative.
  • Alternative names

    • Aristolochic acid III
  • Biological description

    Mycotoxin. Aristolochic acid derivative (Asc 2618). Possible mutagenic and nephrotoxic agent as a constituent aristolochic acid.
  • Purity

    > 95%
  • CAS Number

    4849-90-5
  • Chemical structure

    Chemical Structure

Properties

  • Chemical name

    10-Hydroxy-6-nitronaphtho[2,1-g][1,3]benzodioxole-5-carboxylic acid
  • Molecular weight

    327.25
  • Molecular formula

    C16H9NO7
  • PubChem identifier

    165274
  • Storage instructions

    Store at -20°C. Store under desiccating conditions. The product can be stored for up to 12 months.
  • Solubility overview

    Soluble in DMSO and in ethanol
  • Handling

    Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.

    Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

  • SMILES

    C1OC2=C(O1)C3=C4C=C(C=CC4=CC(=C3C(=C2)C(=O)O)[N+](=O)[O-])O
  • Source

    Aristolochic fangchi

  • Research areas

References

This product has been referenced in:

  • Stiborová M  et al. Human hepatic and renal microsomes, cytochromes P450 1A1/2, NADPH:cytochrome P450 reductase and prostaglandin H synthase mediate the formation of aristolochic acid-DNA adducts found in patients with urothelial cancer. Int J Cancer 113:189-97 (2005). Read more (PubMed: 15386410) »
  • Wu TS  et al. Aristolochic acids, aristolactam alkaloids and amides from Aristolochia kankauensis. Phytochemistry 36:1063-8 (1994). Read more (PubMed: 7765207) »
  • Kupchan SM  et al. Tumor inhibitors. XI. Proof of structure of aristolochic acid-C by total synthesis of its methyl ester methyl ether. J Org Chem 30:3935-7 (1965). Read more (PubMed: 5846162) »

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