- Datasheet
- Specific References
- Protocols
Overview
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Product nameAnti-ARL13B antibody
See all ARL13B primary antibodies -
DescriptionRabbit polyclonal to ARL13B
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Host speciesRabbit
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Tested applicationsSuitable for: WB, IHC-Pmore details
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Species reactivityReacts with: Mouse, Human
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Immunogen
A recombinant fragment corresponding to a region within amino acids 141 and 428 of Human ARL13B
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Positive control
- 293T cell lysate; Mouse liver tissue lysate; Paraffin-embedded U87 xenograft
Properties
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FormLiquid
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Storage instructionsShipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
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Storage bufferpH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 0.75% Glycine, 1.21% Tris, 20% Glycerol -
Concentration information loading... -
PurityImmunogen affinity purified
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ClonalityPolyclonal
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IsotypeIgG
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Research areas
Associated products
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Compatible Secondaries
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Positive Controls
Applications
Our Abpromise guarantee covers the use of ab153725 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB | 1/500 - 1/3000. Predicted molecular weight: 48 kDa. | |
| IHC-P | 1/100 - 1/1000. |
Target
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Involvement in diseaseDefects in ARL13B are the cause of Joubert syndrome type 8 (JBTS8) [MIM:612291]. JBTS is an autosomal recessive disorder presenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay. Neuroradiologically, it is characterized by cerebellar vermis hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth sign). Additional variable features include retinal dystrophy and renal disease.
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Sequence similaritiesBelongs to the small GTPase superfamily. Arf family.
- Information by UniProt
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Database links
- Entrez Gene: 200894 Human
- Entrez Gene: 68146 Mouse
- Omim: 608922 Human
- SwissProt: Q3SXY8 Human
- SwissProt: Q640N2 Mouse
- Unigene: 533086 Human
- Unigene: 96833 Mouse
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Alternative names
- ADP ribosylation factor like 13B antibody
- ADP ribosylation factor like 2 like 1 antibody
- ADP-ribosylation factor-like protein 13B antibody
see all
Images
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Western blot - Anti-ARL13B antibody (ab153725)Anti-ARL13B antibody (ab153725) at 1/1000 dilution + 293T cell lysate at 30 µg
Predicted band size: 48 kDa
10% SDS PAGE -
Western blot - Anti-ARL13B antibody (ab153725)Anti-ARL13B antibody (ab153725) at 1/1000 dilution + Mouse liver tissue lysate at 50 µg
Predicted band size: 48 kDa
10% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ARL13B antibody (ab153725)Immunohistochemical analysis of paraffin-embedded U87 xenograft, labeling ARL13B using ab153725 at 1/500 dilution.
References
ab153725 has not yet been referenced specifically in any publications.
Customer reviews and Q&As
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"