Anti-ARL13B antibody (ab153725)
Key features and details
- Rabbit polyclonal to ARL13B
- Suitable for: WB, IHC-P
- Reacts with: Mouse, Human
- Isotype: IgG
Overview
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Product name
Anti-ARL13B antibody
See all ARL13B primary antibodies -
Description
Rabbit polyclonal to ARL13B -
Host species
Rabbit -
Tested applications
Suitable for: WB, IHC-Pmore details -
Species reactivity
Reacts with: Mouse, Human -
Immunogen
A recombinant fragment corresponding to a region within amino acids 141 and 428 of Human ARL13B
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Positive control
- 293T cell lysate; Mouse liver tissue lysate; Paraffin-embedded U87 xenograft
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General notes
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
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Properties
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Form
Liquid -
Storage instructions
Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle. -
Storage buffer
pH: 7.00
Preservative: 0.01% Thimerosal (merthiolate)
Constituents: 1.21% Tris, 0.75% Glycine, 20% Glycerol (glycerin, glycerine) -
Concentration information loading... -
Purity
Immunogen affinity purified -
Clonality
Polyclonal -
Isotype
IgG -
Research areas
Associated products
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Compatible Secondaries
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Isotype control
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Positive Controls
Applications
The Abpromise guarantee
Our Abpromise guarantee covers the use of ab153725 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| Application | Abreviews | Notes |
|---|---|---|
| WB |
1/500 - 1/3000. Predicted molecular weight: 48 kDa.
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| IHC-P |
1/100 - 1/1000.
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| Notes |
|---|
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WB
1/500 - 1/3000. Predicted molecular weight: 48 kDa. |
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IHC-P
1/100 - 1/1000. |
Target
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Involvement in disease
Defects in ARL13B are the cause of Joubert syndrome type 8 (JBTS8) [MIM:612291]. JBTS is an autosomal recessive disorder presenting with cerebellar ataxia, oculomotor apraxia, hypotonia, neonatal breathing abnormalities and psychomotor delay. Neuroradiologically, it is characterized by cerebellar vermis hypoplasia/aplasia, thickened and reoriented superior cerebellar peduncles, and an abnormally large interpeduncular fossa, giving the appearance of a molar tooth on transaxial slices (molar tooth sign). Additional variable features include retinal dystrophy and renal disease. -
Sequence similarities
Belongs to the small GTPase superfamily. Arf family. - Information by UniProt
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Database links
- Entrez Gene: 200894 Human
- Entrez Gene: 68146 Mouse
- Omim: 608922 Human
- SwissProt: Q3SXY8 Human
- SwissProt: Q640N2 Mouse
- Unigene: 533086 Human
- Unigene: 96833 Mouse
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Alternative names
- ADP ribosylation factor like 13B antibody
- ADP ribosylation factor like 2 like 1 antibody
- ADP-ribosylation factor-like protein 13B antibody
see all
Images
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Western blot - Anti-ARL13B antibody (ab153725)Anti-ARL13B antibody (ab153725) at 1/1000 dilution + 293T cell lysate at 30 µg
Predicted band size: 48 kDa
10% SDS PAGE -
Western blot - Anti-ARL13B antibody (ab153725)Anti-ARL13B antibody (ab153725) at 1/1000 dilution + Mouse liver tissue lysate at 50 µg
Predicted band size: 48 kDa
10% SDS PAGE -
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-ARL13B antibody (ab153725)Immunohistochemical analysis of paraffin-embedded U87 xenograft, labeling ARL13B using ab153725 at 1/500 dilution.
Protocols
Datasheets and documents
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SDS download
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Datasheet download
References (0)
ab153725 has not yet been referenced specifically in any publications.