Overview

  • Product name

    Anti-ARL6IP1 antibody
  • Description

    Rabbit polyclonal to ARL6IP1
  • Host species

    Rabbit
  • Tested applications

    Suitable for: ICC/IF, WB, IHC-Pmore details
  • Species reactivity

    Reacts with: Mouse, Human
  • Immunogen

    Synthetic peptide corresponding to Human ARL6IP1 (C terminal).
    Database link: Q15041

  • General notes

    Previously labelled as ARMER.

Properties

  • Form

    Liquid
  • Storage instructions

    Shipped at 4°C. Store at +4°C.
  • Storage buffer

    Preservative: 0.02% Sodium azide
    Constituent: PBS
  • Concentration information loading...
  • Purification notes

    Ion exchange chromatography purified IgG
  • Clonality

    Polyclonal
  • Isotype

    IgG
  • Research areas

Applications

Our Abpromise guarantee covers the use of ab24228 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
ICC/IF Use a concentration of 20 µg/ml.
WB Use a concentration of 0.5 - 2 µg/ml. Detects a band of approximately 27 kDa (predicted molecular weight: 23 kDa).
IHC-P Use at an assay dependent concentration.

Target

  • Function

    May be involved in protein transport, membrane trafficking, or cell signaling during hematopoietic maturation.
  • Tissue specificity

    Expressed in all hematopoietic cell lineages, but the highest level of expression is found in early myeloid progenitor cells. Expressed in brain, bone marrow, thymus and lung. Expressed at low level in liver, kidney and spleen. Not detected in heart.
  • Sequence similarities

    Belongs to the ARL6ip family.
  • Developmental stage

    Down-regulated during myeloid differentiation.
  • Cellular localization

    Endomembrane system. Predominantly localized to intracytoplasmic membranes.
  • Information by UniProt
  • Database links

  • Alternative names

    • ADP ribosylation factor like 6 interacting protein antibody
    • ADP-ribosylation factor-like protein 6-interacting protein 1 antibody
    • Aip-1 antibody
    • Aip1 antibody
    • AR6P1_HUMAN antibody
    • ARL-6-interacting protein 1 antibody
    • ARL6 interacting protein 1 antibody
    • ARL6IP antibody
    • Arl6ip1 antibody
    • ARMER antibody
    • KIAA0069 antibody
    see all

Images

  • Lane 1 : Anti-ARL6IP1 antibody (ab24228) at 0.5 µg/ml
    Lane 2 : Anti-ARL6IP1 antibody (ab24228) at 1 µg/ml
    Lane 3 : Anti-ARL6IP1 antibody (ab24228) at 2 µg/ml

    All lanes : Human bladder cell lysate

    Predicted band size: 23 kDa
    Observed band size: 27 kDa
    why is the actual band size different from the predicted?



    Western blot ana-lysis of ARL6IP1 in human bladder cell lysates with anti-ARL6IP1 at (A) 0.5, (B) 1, and (C) 2 µg/ml.

  • ab24228 at 2µg/ml staining of ARL6IP1 in human dladder tissue by IHC

References

This product has been referenced in:

  • Huang HY  et al. The embryonic expression patterns and the knockdown phenotypes of zebrafish ADP-ribosylation factor-like 6 interacting protein gene. Dev Dyn 238:232-40 (2009). Read more (PubMed: 19097054) »
See 1 Publication for this product

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