Overview

  • Product name

  • Description

    Rabbit polyclonal to ARMS2
  • Host species

    Rabbit
  • Tested applications

    Suitable for: IHC-Fr, WBmore details
  • Species reactivity

    Reacts with: Human
  • Immunogen

    Synthetic peptide derived from N terminal of human ARMS2

Properties

Applications

Our Abpromise guarantee covers the use of ab80266 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

Application Abreviews Notes
IHC-Fr 1/50 - 1/500.
WB 1/200 - 1/2000. Predicted molecular weight: 11 kDa.

Target

  • Relevance

    ARMS2 is thought to play a role in diseases in the elderly. Mutations in this gene have been associated with age-related macular degeneration (ARMD). ARMD is the most common cause of irreversible vision loss. In most patients, the disease is manifest as ophthalmoscopically visible yellowish accumulations of protein and lipid (known as drusen) that lie beneath the retinal pigment epithelium and within an elastin containing structure known as Bruch's membrane. ARMD is likely to be a mechanistically heterogeneous group of disorders, and the specific disease mechanisms that underlie the vast majority of cases are currently unknown. However, studies have suggested that both genetic and environmental factors may be implicated.
  • Cellular localization

    Cytoplasmic
  • Database links

  • Alternative names

    • Age related maculopathy susceptibility 2 antibody
    • Age related maculopathy susceptibility protein 2 mitochondrial antibody
    • ARMD8 antibody
    • ARMS2 age related maculopathy susceptibility 2 antibody
    • ARMS2 antibody
    • LOC387715 antibody
    • Macular degeneration age related 8 antibody
    see all

References

ab80266 has not yet been referenced specifically in any publications.

Customer reviews and Q&As

Question
Answer

Thank you for contacting us. The immunogen for this antibody is within amino acids 1-50 of human ARMS2. Unfortunately, the exact sequence details are proprietary and we are not able to provide any more specific information. I hope this helps, please let me know if you have any additional questions.

Read More

Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES"
For licensing inquiries, please contact partnerships@abcam.com

Sign up